Tan Lab | DSigDB

Gene Set: D4 : CTD - perfluorooctane sulfonic acid

Collection

D4 : CTD

Chemical Name

perfluorooctane sulfonic acid ( From PubChem : PERFLUOROOCTANESULFONIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
500.13 g/mol	1	3	5.9219	False(2/4)

Structure

InChI

InChI=1S/C8HF17O3S/c9-1(10,3(13,14)5(17,18)7(21,22)23)2(11,12)4(15,16)6(19,20)8(24,25)29(26,27)28/h(H,26,27,28)

InChIKey

YFSUTJLHUFNCNZ-UHFFFAOYSA-N

Links

Gene (71 / 98)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCA1		C076994
CTD	decreases(activity)			ABCB1		C076994
CTD	increases(expression)			ABCB11		C076994
CTD	increases(expression)			ABCB4		C076994
CTD	decreases(activity)			ABCC1		C076994
CTD	decreases(activity)			ABCC4		C076994
CTD	decreases(activity)			ABCG2		C076994
CTD	increases(expression)			ALAS1		C076994
CTD	increases(expression)			ALDH1A1		C076994
CTD	affects(expression)			ANGPTL4		C076994
CTD	increases(expression)			APOA2		C076994
CTD	decreases(expression)			ARG1		C076994
CTD	decreases(expression)			BCL2		C076994
CTD	increases(expression)			CASP9		C076994
CTD	increases(activity)			CAT		C076994
CTD	decreases(expression)			CPS1		C076994
CTD	increases(expression)			CPT1A		C076994
CTD	decreases(reaction)			CXCL8		C076994
CTD	increases(expression)			CXCL8		C076994
CTD	increases(secretion)			CXCL8		C076994
CTD	increases(expression)			CYP11A1		C076994
CTD	increases(expression)			CYP11B2		C076994
CTD	decreases(expression)			CYP17A1		C076994
CTD	increases(expression)			CYP19A1		C076994
CTD	decreases(reaction)			CYP1A2		C076994
CTD	increases(oxidation)			CYP1A2		C076994
CTD	decreases(expression)			CYP21A2		C076994
CTD	decreases(reaction)			CYP2A6		C076994
CTD	increases(hydroxylation)			CYP2A6		C076994
CTD	decreases(reaction)			CYP2B6		C076994
CTD	increases(oxidation)			CYP2B6		C076994
CTD	increases(expression)			CYP2B6		C076994
CTD	decreases(reaction)			CYP2C19		C076994
CTD	increases(oxidation)			CYP2C19		C076994
CTD	increases(expression)			CYP2C19		C076994
CTD	decreases(reaction)			CYP2C8		C076994
CTD	increases(hydroxylation)			CYP2C8		C076994
CTD	decreases(reaction)			CYP2C9		C076994
CTD	increases(hydroxylation)			CYP2C9		C076994
CTD	decreases(reaction)			CYP2D6		C076994
CTD	increases(oxidation)			CYP2D6		C076994
CTD	decreases(reaction)			CYP2E1		C076994
CTD	increases(oxidation)			CYP2E1		C076994
CTD	decreases(reaction)			CYP3A4		C076994
CTD	increases(oxidation)			CYP3A4		C076994
CTD	increases(expression)			CYP3A4		C076994
CTD	affects(binding)			ESR1		C076994
CTD	increases(activity)			ESR1		C076994
CTD	increases(expression)			ESR1		C076994
CTD	increases(expression)			FABP1		C076994
CTD	decreases(activity)			FLT1		C076994
CTD	decreases(activity)			FLT4		C076994
CTD	increases(expression)			GK		C076994
CTD	increases(activity)			GSR		C076994
CTD	increases(expression)			HADHA		C076994
CTD	increases(expression)			HMGCR		C076994
CTD	decreases(activity)			HSD11B1		C076994
CTD	decreases(expression)			HSD17B1		C076994
CTD	decreases(activity)			HSD17B3		C076994
CTD	decreases(expression)			HSD17B4		C076994
CTD	increases(expression)			HSD17B4		C076994
CTD	increases(expression)			HSD3B2		C076994
CTD	increases(expression)			ICAM1		C076994
CTD	decreases(secretion)			IFNG		C076994
CTD	decreases(secretion)			IL10		C076994
CTD	increases(expression)			IL1B		C076994
CTD	decreases(secretion)			IL4		C076994
CTD	decreases(reaction)			IL6		C076994
CTD	increases(secretion)			IL6		C076994
CTD	increases(expression)			IL6		C076994
CTD	increases(expression)			MBL2		C076994
CTD	increases(expression)			NOS3		C076994
CTD	increases(expression)			NR0B2		C076994
CTD	increases(expression)			PCK2		C076994
CTD	increases(expression)			PDK4		C076994
CTD	increases(expression)			PHKA2		C076994
CTD	increases(expression)			PLIN2		C076994
CTD	increases(expression)			POR		C076994
CTD	decreases(reaction)			PPARA		C076994
CTD	increases(activity)			PPARA		C076994
CTD	increases(activity)			PPARA		C076994
CTD	increases(expression)			PPARG		C076994
CTD	increases(expression)			PTGS2		C076994
CTD	decreases(reaction)			RELA		C076994
CTD	increases(activity)			RELA		C076994
CTD	increases(phosphorylation)			RELA		C076994
CTD	increases(expression)			SELP		C076994
CTD	decreases(expression)			SLC25A34		C076994
CTD	increases(expression)			STAR		C076994
CTD	decreases(activity)			TEK		C076994
CTD	decreases(reaction)			TNF		C076994
CTD	increases(expression)			TNF		C076994
CTD	increases(secretion)			TNF		C076994
CTD	increases(expression)			TP53		C076994
CTD	decreases(activity)			TPO		C076994
CTD	affects(expression)			TXNIP		C076994
PubChem	Potency-Replicate_1	uM	6.917	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	47.123	ESR1	-	GI(Protien) :

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