Tan Lab | DSigDB

Gene Set: D4 : CTD - fluazinam

Collection

D4 : CTD

Chemical Name

fluazinam ( From PubChem : FLUAZINAM )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
465.092 g/mol	1	1	7.1054	False(3/4)

Structure

InChI

InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)

InChIKey

Links

Gene (16 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			BAX		C075780
CTD	decreases(expression)			BCL2		C075780
CTD	increases(activity)			CASP3		C075780
CTD	decreases(localization)			SOX17		C075780
CTD	increases(expression)			TP53		C075780
PubChem	AhR Potency (uM)	uM	8.635	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	76.959	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.871	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.635	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.731	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	45.360	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.966	ESR1	-	GI(Protien) :
PubChem	Potency	uM	21.335	EYA2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	23.617	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	25.119	NR1H4	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.776	PPARG	-	GI(Protien) :
PubChem	Potency	uM	1.778	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.025	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.100	TDP1	-	GI(Protien) :
PubChem	Potency	uM	22.387	VDR	-	GI(Protien) :

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