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Gene Set: D4 : CTD - chromium hexavalent ion

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Collection	D4 : CTD
Chemical Name	chromium hexavalent ion ( From PubChem : CHROMIUM(VI) )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 51.9961 g/mol 0 0 0.0 True
Structure
InChI	InChI=1S/Cr/q+6
InChIKey	JOPOVCBBYLSVDA-UHFFFAOYSA-N
Links
Gene (130 / 335) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD affects(localization) AIFM1 C074702 CTD affects(localization) AKT1 C074702 CTD affects(reaction) AKT1 C074702 CTD decreases(reaction) AKT1 C074702 CTD decreases(activity) AKT1 C074702 CTD decreases(phosphorylation) AKT1 C074702 CTD affects(localization) ARNT C074702 CTD decreases(expression) ATP5A1 C074702 CTD increases(phosphorylation) ATR C074702 CTD increases(reaction) ATR C074702 CTD increases(activity) ATR C074702 CTD affects(reaction) ATR C074702 CTD affects(localization) BAX C074702 CTD affects(reaction) BAX C074702 CTD increases(expression) BBC3 C074702 CTD affects(reaction) BBC3 C074702 CTD affects(reaction) BCAR1 C074702 CTD increases(activity) BCAR1 C074702 CTD affects(response to substance) BCL2 C074702 CTD increases(expression) BCL2 C074702 CTD decreases(expression) BCL2L1 C074702 CTD affects(reaction) BCL2L1 C074702 CTD increases(expression) BCL2L11 C074702 CTD increases(expression) BCL9 C074702 CTD decreases(expression) BTD C074702 CTD decreases(reaction) BTD C074702 CTD decreases(reaction) BUB1 C074702 CTD increases(phosphorylation) BUB1 C074702 CTD decreases(expression) BUB1B C074702 CTD decreases(reaction) BUB1B C074702 CTD increases(reaction) BUB1B C074702 CTD increases(activity) CASP2 C074702 CTD affects(reaction) CASP2 C074702 CTD increases(cleavage) CASP3 C074702 CTD increases(reaction) CASP3 C074702 CTD affects(reaction) CASP3 C074702 CTD decreases(reaction) CASP3 C074702 CTD increases(activity) CASP3 C074702 CTD affects(cleavage) CASP3 C074702 CTD increases(activity) CASP3 C074702 CTD increases(activity) CASP3 C074702 CTD increases(cleavage) CASP3 C074702 CTD affects(activity) CASP3 C074702 CTD affects(reaction) CASP3 C074702 CTD affects(reaction) CASP3 C074702 CTD increases(activity) CASP3 C074702 CTD increases(cleavage) CASP7 C074702 CTD increases(reaction) CASP7 C074702 CTD increases(activity) CASP7 C074702 CTD affects(reaction) CASP7 C074702 CTD increases(activity) CASP9 C074702 CTD decreases(reaction) CASP9 C074702 CTD increases(reaction) CASP9 C074702 CTD affects(activity) CAT C074702 CTD decreases(expression) CAT C074702 CTD decreases(reaction) CAT C074702 CTD decreases(reaction) CAT C074702 CTD increases(activity) CAT C074702 CTD decreases(reaction) CAT C074702 CTD increases(chemical synthesis) CAT C074702 CTD decreases(reaction) CAT C074702 CTD increases(activity) CAT C074702 CTD increases(expression) CAT C074702 CTD increases(expression) CAT C074702 CTD decreases(response to substance) CAT C074702 CTD increases(expression) CAT C074702 CTD increases(expression) CCNB1 C074702 CTD increases(expression) CD80 C074702 CTD increases(expression) CD86 C074702 CTD decreases(expression) CDC25B C074702 CTD decreases(expression) CDH1 C074702 CTD decreases(reaction) CDH1 C074702 CTD affects(binding) CDH1 C074702 CTD increases(reaction) CDH1 C074702 CTD decreases(expression) CDK2 C074702 CTD decreases(expression) CDK4 C074702 CTD decreases(expression) CDK6 C074702 CTD affects(localization) CDKN1B C074702 CTD affects(reaction) CDKN1B C074702 CTD decreases(reaction) CDKN1B C074702 CTD decreases(expression) CDKN1B C074702 CTD increases(expression) CDKN2A C074702 CTD increases(expression) CDKN2D C074702 CTD affects(cotreatment) CDT1 C074702 CTD decreases(expression) CDT1 C074702 CTD decreases(phosphorylation) CDT1 C074702 CTD decreases(expression) COX2 C074702 CTD decreases(reaction) CTNNB1 C074702 CTD increases(activity) CTNNB1 C074702 CTD increases(expression) CTNNB1 C074702 CTD decreases(expression) CTNNB1 C074702 CTD increases(expression) CXCL8 C074702 CTD decreases(reaction) CXCL8 C074702 CTD increases(expression) CXCR4 C074702 CTD increases(expression) CYBA C074702 CTD increases(expression) CYBB C074702 CTD affects(localization) DIABLO C074702 CTD affects(reaction) DIABLO C074702 CTD decreases(expression) EGFR C074702 CTD increases(expression) EGFR C074702 CTD affects(localization) ENDOG C074702 CTD increases(expression) ENO2 C074702 CTD affects(expression) ERBB2 C074702 CTD affects(expression) ERBB3 C074702 CTD increases(expression) FABP3 C074702 CTD increases(response to substance) FANCA C074702 CTD increases(activity) FANCD2 C074702 CTD increases(ubiquitination) FANCD2 C074702 CTD affects(cotreatment) FBXO5 C074702 CTD decreases(expression) FBXO5 C074702 CTD decreases(expression) FN1 C074702 CTD decreases(reaction) FYN C074702 CTD increases(activity) FYN C074702 CTD increases(activity) FYN C074702 CTD increases(activity) FYN C074702 CTD increases(expression) FYN C074702 CTD increases(reaction) FYN C074702 CTD increases(phosphorylation) FYN C074702 CTD affects(cotreatment) GMNN C074702 CTD increases(ubiquitination) GMNN C074702 CTD increases(expression) GPM6B C074702 CTD decreases(expression) GPX1 C074702 CTD increases(response to substance) GSR C074702 CTD affects(binding) HDAC1 C074702 CTD increases(reaction) HDAC1 C074702 CTD decreases(reaction) HIF1A C074702 CTD increases(stability) HIF1A C074702 CTD affects(cotreatment) HIF1A C074702 CTD increases(expression) HIF1A C074702 CTD decreases(reaction) HIF1A C074702 CTD increases(expression) HIF1A C074702 CTD increases(stability) HIF1A C074702 CTD affects(localization) HIF1A C074702 CTD increases(expression) HIF1A C074702 CTD increases(expression) HIF1A C074702 CTD decreases(reaction) HIF1A C074702 CTD affects(reaction) HIF1A C074702 CTD affects(expression) HLCS C074702 CTD increases(expression) HLCS C074702 CTD increases(reaction) HLCS C074702 CTD decreases(reaction) HLCS C074702 CTD affects(expression) HMOX1 C074702 CTD increases(expression) HMOX1 C074702 CTD increases(mutagenesis) HPRT1 C074702 CTD increases(expression) ICAM1 C074702 CTD increases(expression) IFNG C074702 CTD decreases(response to substance) IFNG C074702 CTD increases(expression) IGF1R C074702 CTD decreases(reaction) IGF1R C074702 CTD increases(expression) IL2 C074702 CTD increases(expression) IL4 C074702 CTD increases(expression) IL6 C074702 CTD increases(expression) IL6 C074702 CTD affects(reaction) IL6 C074702 CTD decreases(reaction) IRF7 C074702 CTD increases(expression) IRF7 C074702 CTD increases(reaction) IRF7 C074702 CTD affects(reaction) IRF7 C074702 CTD increases(expression) IRS1 C074702 CTD decreases(reaction) IRS1 C074702 CTD increases(expression) KLF8 C074702 CTD increases(activity) LCK C074702 CTD affects(reaction) LCK C074702 CTD increases(expression) LCK C074702 CTD increases(phosphorylation) LCK C074702 CTD increases(expression) LDHA C074702 CTD affects(binding) MAP3K5 C074702 CTD decreases(reaction) MAP3K5 C074702 CTD increases(expression) MAP3K7CL C074702 CTD decreases(reaction) MAPK1 C074702 CTD increases(phosphorylation) MAPK1 C074702 CTD increases(phosphorylation) MAPK1 C074702 CTD increases(phosphorylation) MAPK14 C074702 CTD decreases(reaction) MAPK3 C074702 CTD increases(phosphorylation) MAPK3 C074702 CTD increases(phosphorylation) MAPK3 C074702 CTD decreases(reaction) MAPK8 C074702 CTD increases(activity) MAPK8 C074702 CTD affects(reaction) MAPK8 C074702 CTD increases(phosphorylation) MAPK8 C074702 CTD increases(phosphorylation) MAPK9 C074702 CTD decreases(expression) MIR143 C074702 CTD affects(response to substance) MIR143 C074702 CTD decreases(reaction) MIR143 C074702 CTD increases(expression) MIR143 C074702 CTD increases(localization) MIR143 C074702 CTD decreases(response to substance) MLH1 C074702 CTD increases(reaction) MLH1 C074702 CTD decreases(expression) MLH1 C074702 CTD affects(activity) MLH1 C074702 CTD affects(reaction) MLH1 C074702 CTD increases(activity) MLH1 C074702 CTD increases(cleavage) MLH1 C074702 CTD increases(reaction) MLH1 C074702 CTD increases(response to substance) MLH1 C074702 CTD affects(cotreatment) MLH1 C074702 CTD increases(response to substance) MLH1 C074702 CTD increases(expression) MMP9 C074702 CTD increases(reaction) MSH2 C074702 CTD increases(response to substance) MSH2 C074702 CTD affects(cotreatment) MSH2 C074702 CTD increases(response to substance) MSH2 C074702 CTD increases(response to substance) MSH6 C074702 CTD decreases(reaction) MT1A C074702 CTD increases(expression) MT1A C074702 CTD affects(binding) MT1A C074702 CTD decreases(reaction) MT2A C074702 CTD increases(expression) MT2A C074702 CTD affects(binding) MTF1 C074702 CTD decreases(reaction) MTF1 C074702 CTD decreases(activity) MTF1 C074702 CTD decreases(response to substance) MTF1 C074702 CTD increases(expression) MTSS1 C074702 CTD increases(expression) MYC C074702 CTD affects(localization) NCF1 C074702 CTD increases(activity) NCF1 C074702 CTD increases(expression) NCF1 C074702 CTD increases(phosphorylation) NCF1 C074702 CTD affects(reaction) NCF1 C074702 CTD increases(abundance) NCF1 C074702 CTD affects(response to substance) NCF1 C074702 CTD affects(localization) NCF2 C074702 CTD increases(activity) NCF2 C074702 CTD increases(expression) NCF2 C074702 CTD increases(expression) NCF4 C074702 CTD decreases(expression) NDUFS3 C074702 CTD increases(expression) NOX1 C074702 CTD increases(expression) NOX3 C074702 CTD increases(expression) NOX5 C074702 CTD decreases(expression) NR3C1 C074702 CTD affects(expression) OGG1 C074702 CTD increases(cleavage) PARP1 C074702 CTD increases(reaction) PARP1 C074702 CTD increases(cleavage) PARP1 C074702 CTD affects(reaction) PARP1 C074702 CTD increases(cleavage) PARP1 C074702 CTD affects(reaction) PARP1 C074702 CTD increases(cleavage) PARP1 C074702 CTD increases(expression) PDE3A C074702 CTD increases(expression) PILRA C074702 CTD increases(expression) PMAIP1 C074702 CTD affects(reaction) PMAIP1 C074702 CTD increases(oxidation) PRDX1 C074702 CTD increases(oxidation) PRDX3 C074702 CTD increases(expression) PTGS2 C074702 CTD affects(reaction) RAD17 C074702 CTD increases(phosphorylation) RAD17 C074702 CTD increases(reaction) RAD17 C074702 CTD affects(localization) RB1 C074702 CTD affects(reaction) RB1 C074702 CTD decreases(reaction) RB1 C074702 CTD increases(localization) RELA C074702 CTD decreases(reaction) RELA C074702 CTD decreases(expression) SDHA C074702 CTD increases(phosphorylation) SMC1A C074702 CTD increases(reaction) SMC1A C074702 CTD affects(reaction) SMC1A C074702 CTD affects(expression) SNAI1 C074702 CTD increases(expression) SNAI2 C074702 CTD decreases(expression) SOD1 C074702 CTD increases(expression) SOD1 C074702 CTD decreases(response to substance) SOD1 C074702 CTD increases(expression) SOD2 C074702 CTD decreases(response to substance) SOD2 C074702 CTD decreases(reaction) SRC C074702 CTD increases(phosphorylation) SRC C074702 CTD increases(activity) STAT1 C074702 CTD affects(localization) STAT1 C074702 CTD increases(phosphorylation) STAT1 C074702 CTD increases(phosphorylation) STAT1 C074702 CTD increases(reaction) STAT1 C074702 CTD affects(reaction) STAT1 C074702 CTD decreases(reaction) STAT1 C074702 CTD increases(expression) STAT1 C074702 CTD increases(stability) STAT1 C074702 CTD decreases(expression) STAT1 C074702 CTD affects(reaction) STAT1 C074702 CTD increases(expression) STAT1 C074702 CTD affects(response to substance) STAT1 C074702 CTD affects(localization) STAT3 C074702 CTD increases(activity) STAT3 C074702 CTD increases(phosphorylation) STAT3 C074702 CTD affects(reaction) STAT3 C074702 CTD increases(expression) TFR2 C074702 CTD increases(expression) TNFRSF25 C074702 CTD affects(reaction) TP53 C074702 CTD decreases(reaction) TP53 C074702 CTD increases(activity) TP53 C074702 CTD affects(binding) TP53 C074702 CTD increases(mutagenesis) TP53 C074702 CTD decreases(expression) TP53 C074702 CTD increases(abundance) TP53 C074702 CTD increases(activity) TP53 C074702 CTD increases(activity) TP53 C074702 CTD increases(expression) TP53 C074702 CTD increases(expression) TP53 C074702 CTD increases(phosphorylation) TP53 C074702 CTD decreases(expression) TP53 C074702 CTD decreases(reaction) TP53 C074702 CTD increases(reaction) TP53 C074702 CTD affects(localization) TP53 C074702 CTD decreases(expression) TP53 C074702 CTD increases(expression) TP53 C074702 CTD increases(response to substance) TP53 C074702 CTD decreases(expression) TWIST1 C074702 CTD affects(binding) TXN C074702 CTD decreases(reaction) TXN C074702 CTD increases(oxidation) TXN C074702 CTD increases(oxidation) TXN C074702 CTD increases(oxidation) TXN2 C074702 CTD decreases(reaction) TXN2 C074702 CTD increases(oxidation) TXN2 C074702 CTD decreases(expression) UQCRC2 C074702 CTD decreases(reaction) VDAC1 C074702 CTD increases(expression) VDAC1 C074702 CTD affects(expression) VDAC1 C074702 CTD decreases(abundance) VDAC1 C074702 CTD decreases(reaction) VDAC1 C074702 CTD increases(expression) VDAC1 C074702 CTD decreases(reaction) VEGFA C074702 CTD increases(expression) VEGFA C074702 CTD increases(secretion) VEGFA C074702 CTD decreases(expression) VEGFA C074702 CTD affects(reaction) VEGFA C074702 CTD decreases(reaction) VIM C074702 CTD increases(expression) VIM C074702 CTD affects(localization) WRN C074702 CTD increases(response to substance) WRN C074702 CTD decreases(response to substance) WRN C074702 CTD decreases(reaction) XRCC1 C074702 CTD increases(response to substance) XRCC1 C074702 CTD increases(response to substance) XRCC1 C074702 CTD decreases(activity) YES1 C074702 CTD increases(expression) ZBTB10 C074702 CTD increases(expression) ZEB1 C074702
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