Tan Lab | DSigDB

Gene Set: D4 : CTD - A 771726

Collection

D4 : CTD

Chemical Name

A 771726 ( From PubChem : TERIFLUNOMIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
270.207 g/mol	2	4	3.07248	True

Structure

InChI

InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-

InChIKey

Links

Gene (20 / 39)

⊖ Less

Source	Type	Gene	Other
CTD	decreases(phosphorylation)	AKT1	C072876
CTD	increases(expression)	CCNA2	C072876
CTD	decreases(expression)	CCND2	C072876
CTD	decreases(expression)	CCNE1	C072876
CTD	increases(expression)	CCNE1	C072876
CTD	decreases(expression)	CDC25A	C072876
CTD	increases(expression)	CDKN1A	C072876
CTD	decreases(expression)	CXCR1	C072876
CTD	affects(reaction)	DHODH	C072876
CTD	decreases(reaction)	DHODH	C072876
CTD	increases(oxidation)	DHODH	C072876
CTD	decreases(phosphorylation)	EIF4EBP1	C072876
CTD	increases(expression)	GYPA	C072876
CTD	decreases(reaction)	GYPA	C072876
CTD	increases(expression)	IL10RA	C072876
CTD	decreases(reaction)	LCK	C072876
CTD	increases(activity)	LCK	C072876
CTD	decreases(reaction)	MAP2K1	C072876
CTD	increases(activity)	MAP2K1	C072876
CTD	affects(binding)	NFKB1	C072876
CTD	decreases(reaction)	NFKB1	C072876
CTD	increases(activity)	NFKB1	C072876
CTD	increases(expression)	NFKB1	C072876
CTD	decreases(reaction)	NFKBIA	C072876
CTD	increases(degradation)	NFKBIA	C072876
CTD	decreases(expression)	RB1	C072876
CTD	affects(localization)	RELA	C072876
CTD	decreases(reaction)	RELA	C072876
CTD	affects(binding)	RELA	C072876
CTD	increases(activity)	RELA	C072876
CTD	increases(expression)	RELA	C072876
CTD	decreases(phosphorylation)	RPS6KB1	C072876
CTD	affects(localization)	TNF	C072876
CTD	decreases(reaction)	TNF	C072876
CTD	increases(activity)	TNF	C072876
CTD	affects(binding)	TNF	C072876
CTD	increases(degradation)	TNF	C072876
CTD	increases(expression)	TNF	C072876
CTD	increases(expression)	TP53	C072876

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