Tan Lab | DSigDB

Gene Set: D4 : CTD - SK&F 82958

Collection

D4 : CTD

Chemical Name

SK&F 82958 ( From PubChem : CL-APB )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
329.821 g/mol	2	3	3.8651	True

Structure

InChI

InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m1/s1

InChIKey

Links

Gene (15 / 32)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(localization)			DRD1		C071262
CTD	decreases(reaction)			DRD1		C071262
CTD	affects(binding)			DRD1		C071262
CTD	increases(activity)			DRD1		C071262
PubChem	Potency	uM	0.018	DRD1	-	GI(Protien) :
PubChem	Potency	uM	0.022	DRD1	-	GI(Protien) :
PubChem	Potency	uM	7.080	EHMT2	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	Potency	uM	0.398	DRD3	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	AC50_uM	uM	4.735	GFER	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	None	uM		HSP90AA1	-	GI(Protien) :
PubChem	None	uM		HTR5A	-	GI(Protien) :
PubChem	Potency	uM	7.943	KCNH2		GI(Protien) :
PubChem	Potency	uM	7.943	KCNH2		GI(Protien) :
PubChem	None	uM		MLLT3	-	GI(Protien) :
PubChem	Potency	uM	39.811	MPHOSPH8	-	GI(Protien) :
PubChem	None	uM		SLC12A5	-	GI(Protien) :
PubChem	None	uM		SMARCA2	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	22.400	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	7079.500	EHMT2	-	Target : CHEMBL6032
ChEMBL	AC50	nM	4735.000	GFER	-	Target : CHEMBL1741189
ChEMBL	Potency	nM	12589.300	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	14125.400	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	39810.700	MPHOSPH8	-	Target : CHEMBL1741210

Download gene sets