Tan Lab | DSigDB

Gene Set: D4 : CTD - Win 55212-2

Collection

D4 : CTD

Chemical Name

Win 55212-2 ( From PubChem : (5-METHYL-3-(MORPHOLINOMETHYL)-2,3-DIHYDRO-[1,4]OXAZINO[2,3,4-HI]INDOL-6-YL)(NAPHTHALEN-1-YL)METHANONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
426.507 g/mol	0	5	4.5375	True

Structure

InChI

InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1

InChIKey

HQVHOQAKMCMIIM-HXUWFJFHSA-N

Links

Gene (11 / 25)

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Source	Type	Gene	Other
CTD	increases(phosphorylation)	AKT1	C070417
CTD	affects(reaction)	CNR1	C070417
CTD	increases(activity)	CNR1	C070417
CTD	decreases(reaction)	CNR1	C070417
CTD	increases(activity)	CNR1	C070417
CTD	affects(binding)	CNR1	C070417
CTD	increases(activity)	CNR1	C070417
CTD	affects(binding)	CNR1	C070417
CTD	affects(response to substance)	CNR2	C070417
CTD	affects(binding)	CNR2	C070417
CTD	decreases(reaction)	EGFR	C070417
CTD	increases(phosphorylation)	EGFR	C070417
CTD	affects(reaction)	MAPK1	C070417
CTD	increases(activity)	MAPK1	C070417
CTD	increases(phosphorylation)	MAPK1	C070417
CTD	affects(reaction)	MAPK3	C070417
CTD	increases(activity)	MAPK3	C070417
CTD	increases(phosphorylation)	MAPK3	C070417
CTD	increases(phosphorylation)	MAPK8	C070417
CTD	increases(phosphorylation)	MAPK9	C070417
CTD	affects(binding)	PPARA	C070417
CTD	increases(activity)	PPARA	C070417
CTD	increases(expression)	TRIB3	C070417
CTD	decreases(expression)	VEGFA	C070417
CTD	decreases(secretion)	VEGFA	C070417

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