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Gene Set: D4 : CTD - 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester

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Collection	D4 : CTD
Chemical Name	1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester ( From PubChem : 139890-68-9 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 548.496 g/mol 3 14 1.0748 False(2/4)
Structure
InChI	InChI=1S/C25H28N2O12/c1-17(28)38-16-39-25(35)15-27(14-24(33)34)19-7-3-5-9-21(19)37-11-10-36-20-8-4-2-6-18(20)26(12-22(29)30)13-23(31)32/h2-9H,10-16H2,1H3,(H,29,30)(H,31,32)(H,33,34)
InChIKey	ZYOUCRHWAYJCPN-UHFFFAOYSA-N
Links
Gene (45 / 173) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(reaction) AKT1 C070379 CTD increases(activity) AKT1 C070379 CTD increases(phosphorylation) AKT1 C070379 CTD affects(localization) BAX C070379 CTD decreases(reaction) BAX C070379 CTD decreases(expression) BCL2 C070379 CTD decreases(reaction) BCL2 C070379 CTD decreases(expression) BCL2L1 C070379 CTD decreases(reaction) BCL2L1 C070379 CTD decreases(reaction) CAMK1 C070379 CTD increases(phosphorylation) CAMK1 C070379 CTD affects(localization) CAMP C070379 CTD decreases(reaction) CAMP C070379 CTD decreases(reaction) CASP12 C070379 CTD increases(activity) CASP12 C070379 CTD increases(cleavage) CASP12 C070379 CTD decreases(reaction) CASP3 C070379 CTD increases(degradation) CASP3 C070379 CTD decreases(reaction) CASP3 C070379 CTD increases(activity) CASP3 C070379 CTD increases(cleavage) CASP3 C070379 CTD decreases(reaction) CASP3 C070379 CTD increases(activity) CASP3 C070379 CTD increases(cleavage) CASP3 C070379 CTD decreases(reaction) CASP3 C070379 CTD increases(activity) CASP3 C070379 CTD increases(activity) CASP3 C070379 CTD increases(reaction) CASP3 C070379 CTD decreases(reaction) CCL1 C070379 CTD increases(expression) CCL1 C070379 CTD increases(secretion) CCL1 C070379 CTD decreases(reaction) CDH1 C070379 CTD increases(cleavage) CDH1 C070379 CTD decreases(reaction) CFTR C070379 CTD increases(activity) CFTR C070379 CTD decreases(reaction) CHRNA5 C070379 CTD increases(expression) CHRNA5 C070379 CTD decreases(reaction) CHRNA7 C070379 CTD increases(expression) CHRNA7 C070379 CTD affects(cotreatment) COL6A3 C070379 CTD decreases(reaction) COL6A3 C070379 CTD increases(response to substance) COL6A3 C070379 CTD decreases(reaction) CSF2 C070379 CTD increases(secretion) CSF2 C070379 CTD decreases(reaction) CXCL8 C070379 CTD increases(expression) CXCL8 C070379 CTD decreases(reaction) CXCL8 C070379 CTD increases(expression) CXCL8 C070379 CTD increases(reaction) CXCL8 C070379 CTD decreases(reaction) CXCL8 C070379 CTD increases(abundance) CXCL8 C070379 CTD increases(expression) CXCL8 C070379 CTD decreases(reaction) CXCL8 C070379 CTD increases(secretion) CXCL8 C070379 CTD decreases(reaction) CYP1A1 C070379 CTD increases(expression) CYP1A1 C070379 CTD decreases(reaction) CYP1A1 C070379 CTD increases(expression) CYP1A1 C070379 CTD decreases(reaction) CYP1A1 C070379 CTD increases(activity) CYP1A1 C070379 CTD decreases(reaction) CYP1A1 C070379 CTD increases(activity) CYP1A1 C070379 CTD increases(expression) CYP1A1 C070379 CTD decreases(reaction) DDIT3 C070379 CTD increases(expression) DDIT3 C070379 CTD affects(localization) EGF C070379 CTD decreases(reaction) EGF C070379 CTD decreases(reaction) FAS C070379 CTD increases(expression) FAS C070379 CTD decreases(reaction) FASLG C070379 CTD increases(expression) FASLG C070379 CTD affects(localization) FOS C070379 CTD decreases(reaction) FOS C070379 CTD decreases(reaction) HMOX1 C070379 CTD increases(expression) HMOX1 C070379 CTD decreases(reaction) HSPA5 C070379 CTD increases(expression) HSPA5 C070379 CTD decreases(reaction) IL1A C070379 CTD increases(expression) IL1A C070379 CTD decreases(reaction) IL1B C070379 CTD increases(expression) IL1B C070379 CTD decreases(reaction) IL1B C070379 CTD increases(expression) IL1B C070379 CTD increases(reaction) IL1B C070379 CTD decreases(reaction) ITGB2 C070379 CTD increases(activity) ITGB2 C070379 CTD decreases(reaction) ITGB2 C070379 CTD increases(expression) ITGB2 C070379 CTD affects(localization) JUN C070379 CTD decreases(reaction) JUN C070379 CTD affects(cotreatment) MAPK1 C070379 CTD decreases(reaction) MAPK1 C070379 CTD increases(phosphorylation) MAPK1 C070379 CTD increases(reaction) MAPK1 C070379 CTD decreases(reaction) MAPK1 C070379 CTD increases(activity) MAPK1 C070379 CTD increases(phosphorylation) MAPK1 C070379 CTD decreases(reaction) MAPK1 C070379 CTD increases(activity) MAPK1 C070379 CTD decreases(reaction) MAPK1 C070379 CTD increases(phosphorylation) MAPK1 C070379 CTD decreases(reaction) MAPK1 C070379 CTD increases(phosphorylation) MAPK1 C070379 CTD decreases(reaction) MAPK1 C070379 CTD increases(phosphorylation) MAPK1 C070379 CTD decreases(reaction) MAPK1 C070379 CTD increases(phosphorylation) MAPK1 C070379 CTD decreases(reaction) MAPK14 C070379 CTD increases(activity) MAPK14 C070379 CTD increases(phosphorylation) MAPK14 C070379 CTD affects(cotreatment) MAPK3 C070379 CTD decreases(reaction) MAPK3 C070379 CTD increases(phosphorylation) MAPK3 C070379 CTD increases(reaction) MAPK3 C070379 CTD decreases(reaction) MAPK3 C070379 CTD increases(activity) MAPK3 C070379 CTD increases(phosphorylation) MAPK3 C070379 CTD decreases(reaction) MAPK3 C070379 CTD increases(activity) MAPK3 C070379 CTD decreases(reaction) MAPK3 C070379 CTD increases(phosphorylation) MAPK3 C070379 CTD decreases(reaction) MAPK3 C070379 CTD increases(phosphorylation) MAPK3 C070379 CTD decreases(reaction) MAPK3 C070379 CTD increases(phosphorylation) MAPK3 C070379 CTD decreases(reaction) MAPK3 C070379 CTD increases(phosphorylation) MAPK3 C070379 CTD increases(phosphorylation) MAPK8 C070379 CTD increases(reaction) MAPK8 C070379 CTD decreases(reaction) MAPK8 C070379 CTD increases(activity) MAPK8 C070379 CTD increases(phosphorylation) MAPK8 C070379 CTD decreases(reaction) MAPK8 C070379 CTD increases(expression) MAPK8 C070379 CTD decreases(reaction) MAPK8 C070379 CTD increases(activity) MAPK8 C070379 CTD decreases(reaction) MAPK9 C070379 CTD increases(activity) MAPK9 C070379 CTD increases(phosphorylation) MAPK9 C070379 CTD decreases(reaction) MAPK9 C070379 CTD increases(expression) MAPK9 C070379 CTD decreases(reaction) MMP9 C070379 CTD increases(activity) MMP9 C070379 CTD increases(secretion) MMP9 C070379 CTD decreases(reaction) NDRG1 C070379 CTD increases(expression) NDRG1 C070379 CTD decreases(reaction) NOS3 C070379 CTD increases(expression) NOS3 C070379 CTD decreases(reaction) NOS3 C070379 CTD increases(phosphorylation) NOS3 C070379 CTD increases(abundance) NOS3 C070379 CTD decreases(reaction) NR3C1 C070379 CTD increases(phosphorylation) NR3C1 C070379 CTD decreases(reaction) P2RY1 C070379 CTD increases(activity) P2RY1 C070379 CTD increases(phosphorylation) P2RY1 C070379 CTD decreases(reaction) PARP1 C070379 CTD increases(cleavage) PARP1 C070379 CTD decreases(reaction) PARP1 C070379 CTD increases(cleavage) PARP1 C070379 CTD decreases(reaction) PLA2G1B C070379 CTD increases(abundance) PLA2G1B C070379 CTD increases(expression) PLA2G1B C070379 CTD affects(localization) PRKCB C070379 CTD decreases(reaction) PRKCB C070379 CTD decreases(reaction) RAP1A C070379 CTD increases(activity) RAP1A C070379 CTD decreases(reaction) TNF C070379 CTD increases(secretion) TNF C070379 CTD decreases(reaction) VCAM1 C070379 CTD increases(expression) VCAM1 C070379 CTD decreases(reaction) VEGFA C070379 CTD increases(expression) VEGFA C070379
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