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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 2,3',4,4',5-pentachlorobiphenyl

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Collection	D4 : CTD
Chemical Name	2,3',4,4',5-pentachlorobiphenyl ( From PubChem : PCB 118 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 326.433 g/mol 0 0 6.6206 False(3/4)
Structure
InChI	InChI=1S/C12H5Cl5/c13-8-2-1-6(3-10(8)15)7-4-11(16)12(17)5-9(7)14/h1-5H
InChIKey	IUTPYMGCWINGEY-UHFFFAOYSA-N
Links
Gene (15 / 41) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(expression) AHR C070055 CTD increases(reaction) AHR C070055 CTD increases(activity) AHR C070055 CTD decreases(reaction) AR C070055 CTD increases(activity) AR C070055 CTD decreases(reaction) AR C070055 CTD increases(activity) AR C070055 CTD affects(binding) CYBB C070055 CTD increases(reaction) CYBB C070055 CTD increases(expression) CYP11B2 C070055 CTD increases(expression) CYP1A1 C070055 CTD increases(reaction) CYP1A1 C070055 CTD decreases(reaction) CYP1A2 C070055 CTD increases(activity) CYP1A2 C070055 CTD decreases(activity) CYP1A2 C070055 CTD affects(cotreatment) IRF3 C070055 CTD affects(localization) IRF3 C070055 CTD increases(phosphorylation) IRF3 C070055 CTD decreases(expression) IRF3 C070055 CTD decreases(reaction) IRF3 C070055 CTD increases(response to substance) IRF3 C070055 CTD decreases(phosphorylation) MAPK1 C070055 CTD decreases(phosphorylation) MAPK3 C070055 CTD affects(binding) NCF1 C070055 CTD increases(reaction) NCF1 C070055 CTD increases(localization) NCF1 C070055 CTD increases(phosphorylation) NCF1 C070055 CTD decreases(reaction) NCF1 C070055 CTD affects(binding) NR1I2 C070055 CTD increases(activity) NR1I2 C070055 CTD increases(activity) NR1I2 C070055 CTD decreases(reaction) NR3C1 C070055 CTD increases(activity) NR3C1 C070055 CTD affects(cotreatment) OCLN C070055 CTD decreases(expression) OCLN C070055 CTD decreases(expression) OCLN C070055 CTD decreases(reaction) OCLN C070055 CTD decreases(expression) TJP1 C070055 CTD decreases(reaction) TJP1 C070055 CTD affects(cotreatment) TJP2 C070055 CTD decreases(expression) TJP2 C070055
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