Tan Lab | DSigDB

Gene Set: D4 : CTD - carnosol

Collection

D4 : CTD

Chemical Name

carnosol ( From PubChem : CARNOSOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
330.418 g/mol	2	4	4.2869	True

Structure

InChI

InChI=1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14+,20+/m0/s1

InChIKey

XUSYGBPHQBWGAD-LRDNONRASA-N

Links

Gene (25 / 51)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			AHR		C068623
CTD	decreases(reaction)			CYP1A1		C068623
CTD	increases(expression)			CYP1A1		C068623
CTD	decreases(reaction)			CYP1B1		C068623
CTD	increases(expression)			CYP1B1		C068623
CTD	increases(expression)			GCLC		C068623
CTD	increases(expression)			GCLM		C068623
CTD	increases(expression)			HMOX1		C068623
CTD	affects(localization)			HMOX1		C068623
CTD	decreases(reaction)			HMOX1		C068623
CTD	decreases(reaction)			HMOX1		C068623
CTD	increases(expression)			HMOX1		C068623
CTD	increases(glutathionylation)			HMOX1		C068623
CTD	decreases(reaction)			ICAM1		C068623
CTD	increases(expression)			ICAM1		C068623
CTD	decreases(reaction)			IKBKB		C068623
CTD	increases(phosphorylation)			IKBKB		C068623
CTD	increases(localization)			NFE2L2		C068623
CTD	affects(localization)			NFE2L2		C068623
CTD	decreases(reaction)			NFE2L2		C068623
CTD	increases(expression)			NFE2L2		C068623
CTD	increases(glutathionylation)			NFE2L2		C068623
CTD	decreases(reaction)			NFKBIA		C068623
CTD	increases(degradation)			NFKBIA		C068623
CTD	increases(phosphorylation)			NFKBIA		C068623
CTD	affects(localization)			RELA		C068623
CTD	decreases(reaction)			RELA		C068623
CTD	increases(glutathionylation)			RELA		C068623
CTD	affects(localization)			TNF		C068623
CTD	decreases(reaction)			TNF		C068623
CTD	increases(expression)			TNF		C068623
CTD	increases(glutathionylation)			TNF		C068623
CTD	increases(degradation)			TNF		C068623
CTD	increases(phosphorylation)			TNF		C068623
PubChem	Potency	uM	0.891	EHMT2	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	None	uM		MRGPRX1	-	GI(Protien) :
PubChem	None	uM		MRGPRX1	-	GI(Protien) :
PubChem	IC50	uM	2.594	NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		PAFAH1B2	-	GI(Protien) :
PubChem	None	uM		PAFAH2	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	Potency	uM	6.702	PLK1	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	Potency	uM	12.589	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	5.173	TDP1	-	GI(Protien) :
PubChem	Potency	uM	8.200	TDP1	-	GI(Protien) :

Download gene sets

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