Tan Lab | DSigDB

Gene Set: D4 : CTD - SK&F 81297

Collection

D4 : CTD

Chemical Name

SK&F 81297 ( From PubChem : SKF 81297 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
289.757 g/mol	3	3	3.3576	True

Structure

InChI

InChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2/t13-/m0/s1

InChIKey

Links

Gene (7 / 32)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			DRD1		C067113
CTD	decreases(reaction)			DRD1		C067113
CTD	increases(activity)			DRD1		C067113
CTD	increases(phosphorylation)			DRD1		C067113
CTD	increases(reaction)			DRD1		C067113
CTD	affects(localization)			DRD1		C067113
CTD	decreases(reaction)			DRD1		C067113
CTD	affects(binding)			DRD1		C067113
CTD	increases(activity)			DRD1		C067113
CTD	affects(binding)			MAPK1		C067113
CTD	decreases(reaction)			MAPK1		C067113
CTD	increases(activity)			MAPK1		C067113
CTD	increases(phosphorylation)			MAPK1		C067113
CTD	increases(reaction)			MAPK1		C067113
CTD	affects(binding)			MAPK3		C067113
CTD	decreases(reaction)			MAPK3		C067113
CTD	increases(activity)			MAPK3		C067113
CTD	increases(phosphorylation)			MAPK3		C067113
CTD	increases(reaction)			MAPK3		C067113
CTD	affects(binding)			SIGMAR1		C067113
CTD	decreases(reaction)			SIGMAR1		C067113
CTD	increases(activity)			SIGMAR1		C067113
CTD	increases(phosphorylation)			SIGMAR1		C067113
CTD	increases(reaction)			SIGMAR1		C067113
PubChem	Potency	uM	0.006	DRD1	-	GI(Protien) :
PubChem	Potency	uM	0.063	DRD1	-	GI(Protien) :
PubChem	Potency	uM	10.621	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	1.122	GLS	-	GI(Protien) :
PubChem	Potency	uM	8.200	TDP1	-	GI(Protien) :
PubChem	Potency	uM	8.200	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	63.100	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	10621.300	EHMT2	-	Target : CHEMBL6032

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