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Gene Set: D4 : CTD - O-(chloroacetylcarbamoyl)fumagillol

Collection D4 : CTD
Chemical Name O-(chloroacetylcarbamoyl)fumagillol ( From PubChem : [7-METHOXY-8-[2-METHYL-3-(3-METHYLBUT-2-ENYL)OXIRAN-2-YL]-2-OXASPIRO[2.5]OCTAN-6-YL] N-(2-CHLOROACETYL)CARBAMATE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
401.882 g/mol 1 7 2.9453 True
Structure
InChI InChI=1S/C19H28ClNO6/c1-11(2)5-6-13-18(3,27-13)16-15(24-4)12(7-8-19(16)10-25-19)26-17(23)21-14(22)9-20/h5,12-13,15-16H,6-10H2,1-4H3,(H,21,22,23)
InChIKey MSHZHSPISPJWHW-UHFFFAOYSA-N
Links

Gene (9 / 11)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDincreases(expression)CCND1
C066515
CTDincreases(expression)CDKN1A
C066515
CTDaffects(cotreatment)FGF2
C066515
CTDdecreases(expression)FGF2
C066515
CTDaffects(cotreatment)MMP9
C066515
CTDdecreases(expression)MMP9
C066515
CTDdecreases(phosphorylation)RB1
C066515
CTDincreases(expression)TP53
C066515
PubChem Ratio Potency (uM)uM12.423HSPB1-GI(Protien) :
PubChem Ratio Potency (uM)uM2.505NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM5.992PPARG-GI(Protien) :
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