Tan Lab | DSigDB

Gene Set: D4 : CTD - loreclezole

Collection

D4 : CTD

Chemical Name

loreclezole ( From PubChem : LORECLEZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
274.534 g/mol	0	3	3.7793	True

Structure

InChI

InChI=1S/C10H6Cl3N3/c11-7-1-2-8(9(12)3-7)10(13)4-16-6-14-5-15-16/h1-6H/b10-4-

InChIKey

Links

Gene (7 / 24)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			GABRA1		C066440
CTD	affects(cotreatment)			GABRA1		C066440
CTD	increases(activity)			GABRA1		C066440
CTD	increases(reaction)			GABRA1		C066440
CTD	affects(response to substance)			GABRB2		C066440
CTD	increases(reaction)			GABRB2		C066440
CTD	increases(transport)			GABRB2		C066440
CTD	affects(binding)			GABRB3		C066440
CTD	affects(cotreatment)			GABRB3		C066440
CTD	increases(activity)			GABRB3		C066440
CTD	increases(reaction)			GABRB3		C066440
CTD	affects(response to substance)			GABRB3		C066440
CTD	increases(reaction)			GABRB3		C066440
CTD	increases(transport)			GABRB3		C066440
CTD	affects(binding)			GABRG2		C066440
CTD	affects(cotreatment)			GABRG2		C066440
CTD	increases(activity)			GABRG2		C066440
CTD	increases(reaction)			GABRG2		C066440
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	14.125	HPGD	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
ChEMBL	AC50	nM	63.100	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	14125.400	HPGD	-	Target : CHEMBL1293255

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