Tan Lab | DSigDB

Gene Set: D4 : CTD - bis(tri-n-butyltin)oxide

Collection

D4 : CTD

Chemical Name

bis(tri-n-butyltin)oxide ( From PubChem : TBTO )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
596.087 g/mol	0	1	9.6946	False(2/4)

Structure

InChI

InChI=1S/6C4H9.O.2Sn/c6*1-3-4-2;;;/h6*1,3-4H2,2H3;;;

InChIKey

APQHKWPGGHMYKJ-UHFFFAOYSA-N

Links

Gene (72 / 82)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCA1		C005961
CTD	increases(expression)			ABCG1		C005961
CTD	affects(localization)			ATF3		C005961
CTD	increases(expression)			ATF3		C005961
CTD	increases(expression)			ATF3		C005961
CTD	increases(expression)			BACH2		C005961
CTD	increases(expression)			BAG3		C005961
CTD	increases(expression)			BCL2A1		C005961
CTD	decreases(expression)			BCL2L1		C005961
CTD	increases(expression)			BIRC3		C005961
CTD	increases(cleavage)			CASP3		C005961
CTD	increases(expression)			CASP8		C005961
CTD	increases(expression)			CD44		C005961
CTD	increases(expression)			CD55		C005961
CTD	increases(expression)			CD69		C005961
CTD	increases(expression)			CDKN1A		C005961
CTD	increases(expression)			CREBBP		C005961
CTD	increases(expression)			CYCS		C005961
CTD	increases(expression)			CYP1A1		C005961
CTD	increases(expression)			CYP1A2		C005961
CTD	increases(expression)			DDIT3		C005961
CTD	increases(expression)			DDIT3		C005961
CTD	increases(expression)			DDIT4		C005961
CTD	increases(expression)			DEDD2		C005961
CTD	increases(expression)			DNAJC1		C005961
CTD	increases(expression)			DUSP6		C005961
CTD	increases(expression)			EDEM1		C005961
CTD	increases(expression)			EIF2S1		C005961
CTD	increases(expression)			ERN1		C005961
CTD	increases(expression)			ERO1LB		C005961
CTD	increases(expression)			EVI2A		C005961
CTD	decreases(expression)			EXOSC2		C005961
CTD	decreases(expression)			EXOSC7		C005961
CTD	increases(expression)			FASLG		C005961
CTD	increases(expression)			GADD45A		C005961
CTD	increases(expression)			GADD45B		C005961
CTD	increases(expression)			GCLM		C005961
CTD	decreases(expression)			GEMIN4		C005961
CTD	increases(expression)			GPX2		C005961
CTD	increases(expression)			GPX3		C005961
CTD	increases(expression)			GPX7		C005961
CTD	increases(expression)			GSTT2		C005961
CTD	increases(expression)			HERPUD1		C005961
CTD	affects(localization)			KEAP1		C005961
CTD	increases(expression)			KLF2		C005961
CTD	increases(expression)			MAFG		C005961
CTD	decreases(expression)			MYC		C005961
CTD	affects(localization)			NFATC1		C005961
CTD	decreases(expression)			NOLC1		C005961
CTD	increases(expression)			NR4A1		C005961
CTD	increases(expression)			NR4A1		C005961
CTD	affects(expression)			PDE4DIP		C005961
CTD	increases(expression)			PMAIP1		C005961
CTD	increases(expression)			PTEN		C005961
CTD	increases(expression)			RELA		C005961
CTD	affects(localization)			RELA		C005961
CTD	increases(phosphorylation)			RELA		C005961
CTD	decreases(expression)			RHOH		C005961
CTD	decreases(expression)			RPL27A		C005961
CTD	decreases(expression)			RSL1D1		C005961
CTD	affects(expression)			SERP1		C005961
CTD	decreases(expression)			SHISA2		C005961
CTD	increases(expression)			SIAH2		C005961
CTD	increases(expression)			SIPA1		C005961
CTD	decreases(activity)			SRD5A2		C005961
CTD	increases(expression)			TNFAIP3		C005961
CTD	increases(expression)			TNFRSF1A		C005961
CTD	increases(expression)			TNFSF9		C005961
CTD	increases(expression)			VPREB1		C005961
CTD	increases(expression)			XBP1		C005961
PubChem	Potency-Replicate_1	uM	0.427	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.844	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.670	CYP19A1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.395	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.119	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	27.306	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.339	PPARD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		PPARD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.537	PPARG	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.676	PPARG	-	GI(Protien) :
PubChem	Potency	uM	0.355	RXRA	-	GI(Protien) :
PubChem	Potency	uM	22.387	VDR	-	GI(Protien) :

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