Tan Lab | DSigDB

Gene Set: D4 : CTD - adapalene

Collection

D4 : CTD

Chemical Name

adapalene ( From PubChem : ADAPALENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
412.52 g/mol	1	3	6.6814	False(3/4)

Structure

InChI

InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)/t17-,18+,19-,28-

InChIKey

LZCDAPDGXCYOEH-AADAIPAGSA-N

Links

Gene (13 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			CD1D		C063610
CTD	increases(expression)			CRABP2		C063610
CTD	decreases(expression)			IL10		C063610
CTD	affects(response to substance)			RARG		C063610
CTD	decreases(reaction)			SLC22A2		C063610
CTD	increases(uptake)			SLC22A2		C063610
CTD	decreases(expression)			TLR2		C063610
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	0.162	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.376	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	7.004	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.562	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	29.847	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	11.004	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	10.682	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	79.433	USP1	-	GI(Protien) :

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