Tan Lab | DSigDB

Gene Set: D4 : CTD - carboxyamido-triazole

Collection

D4 : CTD

Chemical Name

carboxyamido-triazole ( From PubChem : CARBOXYAMIDOTRIAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
424.668 g/mol	2	7	4.4802	True

Structure

InChI

InChI=1S/C17H12Cl3N5O2/c18-10-3-1-9(2-4-10)15(26)13-11(19)5-8(6-12(13)20)7-25-16(21)14(17(22)27)23-24-25/h1-6H,7,21H2,(H2,22,27)

InChIKey

Links

Gene (15 / 39)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			AKT1		C062058
CTD	decreases(expression)			AKT1		C062058
CTD	decreases(reaction)			AKT1		C062058
CTD	affects(cotreatment)			CASP3		C062058
CTD	decreases(reaction)			CASP3		C062058
CTD	increases(cleavage)			CASP3		C062058
CTD	affects(cotreatment)			CCND1		C062058
CTD	decreases(expression)			CCND1		C062058
CTD	decreases(reaction)			CCND1		C062058
CTD	affects(cotreatment)			MAPK1		C062058
CTD	decreases(reaction)			MAPK1		C062058
CTD	increases(activity)			MAPK1		C062058
CTD	affects(cotreatment)			MAPK3		C062058
CTD	decreases(reaction)			MAPK3		C062058
CTD	increases(activity)			MAPK3		C062058
CTD	affects(cotreatment)			PARP1		C062058
CTD	decreases(reaction)			PARP1		C062058
CTD	increases(cleavage)			PARP1		C062058
PubChem	Potency	uM	3.162	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	IC50	uM	0.303	GALR3	-	GI(Protien) :
PubChem	IC50	uM	3.436	GALR3	-	GI(Protien) :
PubChem	None	uM		GALR3	-	GI(Protien) :
PubChem	None	uM		GALR3	-	GI(Protien) :
PubChem	Potency	uM	3.162	HIF1A	-	GI(Protien) :
PubChem	Potency	uM	9.200	IDH1	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	IC50	uM	9.206	NR2F2	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		PTGER2	-	GI(Protien) :
PubChem	Potency	uM	4.611	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	3162.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	3162.280	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	3162.300	HIF1A	-	Target : CHEMBL4261

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