Tan Lab | DSigDB

Gene Set: D4 : CTD - dibenzoylmethane

Collection

D4 : CTD

Chemical Name

dibenzoylmethane ( From PubChem : DIBENZOYLMETHANE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
224.255 g/mol	0	2	3.1423	True

Structure

InChI

InChI=1S/C15H12O2/c16-14(12-7-3-1-4-8-12)11-15(17)13-9-5-2-6-10-13/h1-10H,11H2

InChIKey

Links

Gene (15 / 33)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCG2		C061481
CTD	increases(expression)			BAD		C061481
CTD	decreases(reaction)			BAD		C061481
CTD	affects(binding)			BCL2		C061481
CTD	decreases(reaction)			BCL2		C061481
CTD	increases(expression)			BCL2		C061481
CTD	decreases(reaction)			CASP9		C061481
CTD	increases(activity)			CASP9		C061481
CTD	affects(binding)			ESR1		C061481
CTD	decreases(reaction)			ESR1		C061481
CTD	decreases(reaction)			HRAS		C061481
CTD	increases(expression)			HRAS		C061481
CTD	affects(binding)			MYC		C061481
CTD	decreases(reaction)			MYC		C061481
CTD	decreases(reaction)			ODC1		C061481
CTD	increases(abundance)			ODC1		C061481
CTD	increases(activity)			ODC1		C061481
CTD	increases(expression)			ODC1		C061481
CTD	decreases(response to substance)			ODC1		C061481
CTD	affects(binding)			TERT		C061481
CTD	decreases(reaction)			TERT		C061481
CTD	increases(expression)			TERT		C061481
PubChem	AhR Potency (uM)	uM	52.177	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	65.687	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	29.582	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	35.839	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.681	ESR1	-	GI(Protien) :
PubChem	Potency	uM	14.125	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	15.879	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	23.306	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	Potency	uM	12.589	SMN2	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	SMN1; SMN2	-	Target : CHEMBL1293232

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