Tan Lab | DSigDB

Gene Set: D4 : CTD - flusilazole

Collection

D4 : CTD

Chemical Name

flusilazole ( From PubChem : FLUSILAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
315.393 g/mol	0	3	2.2549	True

Structure

InChI

InChI=1S/C16H15F2N3Si/c1-22(12-21-11-19-10-20-21,15-6-2-13(17)3-7-15)16-8-4-14(18)5-9-16/h2-11H,12H2,1H3

InChIKey

Links

Gene (9 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			CYP19A1		C061365
CTD	decreases(activity)			CYP51A1		C061365
CTD	increases(activity)			PPARD		C061365
CTD	decreases(localization)			SOX17		C061365
PubChem	AhR Potency (uM)	uM		AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.147	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.966	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	58.829	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.131	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	63.125	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	63.125	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.316	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.545	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.966	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	52.431	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	54.941	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.131	ESR1	-	GI(Protien) :
PubChem	Potency	uM	22.387	NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	54.941	NR3C1	-	GI(Protien) :

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