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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine

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Collection	D4 : CTD
Chemical Name	2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine ( From PubChem : N-HYDROXY PHIP )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 240.261 g/mol 2 5 2.5094 True
Structure
InChI	InChI=1S/C13H12N4O/c1-17-11-7-10(9-5-3-2-4-6-9)8-14-12(11)15-13(17)16-18/h2-8,18H,1H3,(H,14,15,16)
InChIKey	DCVWQAGUQFBCTF-UHFFFAOYSA-N
Links
Gene (18 / 57) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(chemical synthesis) CYP1A1 C060533 CTD increases(metabolic processing) CYP1A1 C060533 CTD affects(cotreatment) CYP1A1 C060533 CTD increases(chemical synthesis) CYP1A1 C060533 CTD increases(hydroxylation) CYP1A1 C060533 CTD affects(cotreatment) CYP1A2 C060533 CTD increases(chemical synthesis) CYP1A2 C060533 CTD increases(hydroxylation) CYP1A2 C060533 CTD increases(chemical synthesis) CYP1A2 C060533 CTD increases(metabolic processing) CYP1A2 C060533 CTD increases(chemical synthesis) CYP1A2 C060533 CTD increases(metabolic processing) CYP1A2 C060533 CTD increases(chemical synthesis) CYP1B1 C060533 CTD increases(metabolic processing) CYP1B1 C060533 CTD increases(chemical synthesis) CYP2C19 C060533 CTD increases(metabolic processing) CYP2C19 C060533 CTD decreases(reaction) ESR1 C060533 CTD increases(activity) ESR1 C060533 CTD decreases(activity) ESR1 C060533 CTD affects(cotreatment) GSTP1 C060533 CTD decreases(reaction) GSTP1 C060533 CTD increases(activity) GSTP1 C060533 CTD increases(abundance) GSTP1 C060533 CTD increases(metabolic processing) GSTP1 C060533 CTD decreases(response to substance) GSTP1 C060533 CTD affects(acetylation) NAT1 C060533 CTD affects(activity) NAT1 C060533 CTD increases(acetylation) NAT2 C060533 CTD increases(activity) SULT1A1 C060533 CTD increases(metabolic processing) SULT1A1 C060533 CTD increases(glucuronidation) UGT1A C060533 CTD affects(metabolic processing) UGT1A1 C060533 CTD affects(binding) UGT1A1 C060533 CTD affects(reaction) UGT1A1 C060533 CTD increases(reaction) UGT1A1 C060533 CTD increases(glucuronidation) UGT1A1 C060533 CTD decreases(activity) UGT1A1 C060533 CTD increases(glucuronidation) UGT1A1 C060533 CTD increases(metabolic processing) UGT1A1 C060533 CTD increases(glucuronidation) UGT1A10 C060533 CTD increases(glucuronidation) UGT1A3 C060533 CTD affects(binding) UGT1A4 C060533 CTD increases(reaction) UGT1A4 C060533 CTD increases(glucuronidation) UGT1A4 C060533 CTD increases(metabolic processing) UGT1A4 C060533 CTD increases(glucuronidation) UGT1A7 C060533 CTD affects(binding) UGT1A8 C060533 CTD increases(reaction) UGT1A8 C060533 CTD increases(glucuronidation) UGT1A8 C060533 CTD increases(metabolic processing) UGT1A8 C060533 CTD affects(binding) UGT1A9 C060533 CTD increases(reaction) UGT1A9 C060533 CTD increases(glucuronidation) UGT1A9 C060533 CTD increases(metabolic processing) UGT1A9 C060533 CTD affects(binding) UGT2B10 C060533 CTD increases(reaction) UGT2B10 C060533 CTD increases(metabolic processing) UGT2B10 C060533
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