Tan Lab | DSigDB

Gene Set: D4 : CTD - 5,7-dimethoxyflavone

Collection

D4 : CTD

Chemical Name

5,7-dimethoxyflavone ( From PubChem : 5,7-DIMETHOXYFLAVONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
282.291 g/mol	0	4	3.4772	True

Structure

InChI

InChI=1S/C17H14O4/c1-19-12-8-15(20-2)17-13(18)10-14(21-16(17)9-12)11-6-4-3-5-7-11/h3-10H,1-2H3

InChIKey

Links

Gene (12 / 28)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			CYP1A1		C060298
CTD	increases(activity)			CYP1A1		C060298
CTD	increases(expression)			CYP1A1		C060298
CTD	decreases(reaction)			CYP1A1		C060298
CTD	increases(expression)			CYP1A1		C060298
CTD	decreases(reaction)			CYP1A1		C060298
CTD	increases(expression)			CYP1A1		C060298
CTD	decreases(activity)			CYP1A1		C060298
CTD	decreases(reaction)			CYP1B1		C060298
CTD	increases(activity)			CYP1B1		C060298
CTD	decreases(reaction)			CYP1B1		C060298
CTD	increases(expression)			CYP1B1		C060298
CTD	decreases(activity)			CYP1B1		C060298
PubChem	Potency	uM	23.100	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	7.943	BRCA1	-	GI(Protien) :
PubChem	None	uM		CASP3	-	GI(Protien) :
PubChem	None	uM		DLD	-	GI(Protien) :
PubChem	None	uM		HCRTR1	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		NR0B1	-	GI(Protien) :
PubChem	None	uM		SENP6	-	GI(Protien) :
PubChem	None	uM		SENP6	-	GI(Protien) :
PubChem	None	uM		SENP7	-	GI(Protien) :
PubChem	None	uM		SENP7	-	GI(Protien) :
PubChem	None	uM		SENP8	-	GI(Protien) :
PubChem	None	uM		SENP8	-	GI(Protien) :
PubChem	Potency	uM	20.596	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	23099.900	ATAD5	-	Target : CHEMBL1741209

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