Tan Lab | DSigDB

Gene Set: D4 : CTD - tyrphostin 47

Collection

D4 : CTD

Chemical Name

tyrphostin 47 ( From PubChem : AG 213 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
220.248 g/mol	3	5	1.81758	True

Structure

InChI

InChI=1S/C10H8N2O2S/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,14-15H,12H2/b6-3+,10-7+

InChIKey

CTSHLCWTPAQAAB-HCUSPQTFSA-N

Links

Gene (25 / 59)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(activity)			CACNA1H		C060152
PubChem	Potency	uM	2.239	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	8.912	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	12.589	CBX1	-	GI(Protien) :
PubChem	Potency	uM	0.517	DRD1	-	GI(Protien) :
PubChem	Potency	uM	7.519	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	2.994	FEN1	-	GI(Protien) :
PubChem	Potency	uM	2.994	FEN1	-	GI(Protien) :
PubChem	Potency	uM	2.239	MAPT	-	GI(Protien) :
PubChem	Potency	uM	15.849	MAPT	-	GI(Protien) :
PubChem	Potency	uM	13.371	MPHOSPH8	-	GI(Protien) :
PubChem	Potency	uM	0.126	POLK	-	GI(Protien) :
PubChem	Potency	uM	0.794	POLK	-	GI(Protien) :
PubChem	Potency	uM	1.683	POLK	-	GI(Protien) :
PubChem	Potency	uM	6.702	RGS4	-	GI(Protien) :
PubChem	Potency	uM	39.811	VDR	-	GI(Protien) :
PubChem	Potency	uM	12.589	ALOX12	-	GI(Protien) :
PubChem	Potency	uM	1.995	ALOX15	-	GI(Protien) :
PubChem	Potency	uM	3.981	ALOX15	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	25.119	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	Potency	uM	10.000	HIF1A	-	GI(Protien) :
PubChem	Potency	uM	8.912	HPGD	-	GI(Protien) :
PubChem	Potency	uM	15.849	MAPK1	-	GI(Protien) :
PubChem	Potency	uM	15.849	MAPT	-	GI(Protien) :
PubChem	Potency	uM	5.623	NFKB1	-	GI(Protien) :
PubChem	Potency	uM	1.413	POLK	-	GI(Protien) :
PubChem	Potency	uM	18.837	TDP1	-	GI(Protien) :
PubChem	Potency	uM	29.855	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	2238.700	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	8912.500	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	12589.300	ALOX12	-	Target : CHEMBL3687
ChEMBL	Potency	nM	3981.100	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	1995.300	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	25118.900	ALOX15B	-	Target : CHEMBL2457
ChEMBL	AC50	nM	12589.200	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	6309.570	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	25118.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	25118.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	12589.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	12589.200	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	10000.000	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	8912.500	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	12589.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	1258.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	100.000	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	15848.900	MAPK1	-	Target : CHEMBL4040
ChEMBL	Potency	nM	15848.900	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	2238.700	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	5623.400	NFKB1	-	Target : CHEMBL3251
ChEMBL	Potency	nM	5623.400	RECQL	-	Target : CHEMBL1293236

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