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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - N(1),N(11)-diethylnorspermine

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Collection	D4 : CTD
Chemical Name	N(1),N(11)-diethylnorspermine ( From PubChem : DENSPM )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 244.42 g/mol 4 4 2.1185 True
Structure
InChI	InChI=1S/C13H32N4/c1-3-14-8-5-10-16-12-7-13-17-11-6-9-15-4-2/h14-17H,3-13H2,1-2H3
InChIKey	UMJJGDUYVQCBMC-UHFFFAOYSA-N
Links
Gene (13 / 49) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(activity) CASP9 C059685 CTD increases(cleavage) CASP9 C059685 CTD increases(reaction) CASP9 C059685 CTD decreases(reaction) CASP9 C059685 CTD decreases(expression) CCNA2 C059685 CTD increases(reaction) CCNA2 C059685 CTD decreases(reaction) CCNA2 C059685 CTD decreases(expression) CCNB1 C059685 CTD increases(reaction) CCNB1 C059685 CTD decreases(reaction) CCNB1 C059685 CTD increases(expression) CDKN1A C059685 CTD increases(reaction) CDKN1A C059685 CTD increases(expression) FAS C059685 CTD increases(reaction) FAS C059685 CTD increases(expression) MDM2 C059685 CTD increases(reaction) MDM2 C059685 CTD affects(cotreatment) NFKB1 C059685 CTD affects(localization) NFKB1 C059685 CTD affects(binding) NFKB1 C059685 CTD decreases(expression) NFKB1 C059685 CTD affects(cotreatment) NFKBIA C059685 CTD decreases(expression) NFKBIA C059685 CTD affects(reaction) NFKBIA C059685 CTD increases(expression) NFKBIA C059685 CTD increases(reaction) NFKBIA C059685 CTD decreases(activity) ODC1 C059685 CTD affects(binding) RELA C059685 CTD affects(cotreatment) RELA C059685 CTD increases(reaction) RELA C059685 CTD affects(localization) RELA C059685 CTD decreases(expression) RELA C059685 CTD affects(binding) SAT1 C059685 CTD affects(cotreatment) SAT1 C059685 CTD increases(reaction) SAT1 C059685 CTD increases(expression) SAT1 C059685 CTD decreases(reaction) SAT1 C059685 CTD affects(cotreatment) SAT1 C059685 CTD increases(expression) SAT1 C059685 CTD affects(cotreatment) SAT1 C059685 CTD increases(expression) SAT1 C059685 CTD increases(activity) SAT1 C059685 CTD affects(reaction) SAT1 C059685 CTD increases(expression) TP53 C059685 CTD increases(reaction) TP53 C059685 CTD decreases(expression) TP53 C059685 CTD decreases(reaction) TP53 C059685 CTD increases(activity) TP53 C059685 CTD increases(cleavage) TP53 C059685 PubChem Potency uM 3.759 TDP1 - GI(Protien) :
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