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Gene Set: D4 : CTD - 2',4'-dihydroxychalcone

Collection D4 : CTD
Chemical Name 2',4'-dihydroxychalcone ( From PubChem : 2',4'-DIHYDROXYCHALCONE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
240.254 g/mol 2 3 2.9939 True
Structure
InChI InChI=1S/C15H12O3/c16-12-7-8-13(15(18)10-12)14(17)9-6-11-4-2-1-3-5-11/h1-10,16,18H/b9-6+
InChIKey JUMSUVHHUVPSOY-RMKNXTFCSA-N
Links

Gene (12 / 14)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(expression)BIRC5
C059354
CTDincreases(activity)CASP3
C059354
CTDincreases(glucuronidation)UGT1A1
C059354
CTDincreases(glucuronidation)UGT1A10
C059354
CTDincreases(glucuronidation)UGT1A7
C059354
CTDincreases(glucuronidation)UGT1A8
C059354
CTDincreases(glucuronidation)UGT1A9
C059354
PubChem PotencyuM19.953ALOX15-GI(Protien) :
PubChem PotencyuM15.849HPGD-GI(Protien) :
PubChem PotencyuM16.360TDP1-GI(Protien) :
PubChem PotencyuM25.119VDR-GI(Protien) :
ChEMBLInhibition-ABCB1
-Target : CHEMBL4302
ChEMBLPotencynM19952.600ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM15848.900HPGD
-Target : CHEMBL1293255
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