DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : CTD - ebastine

Collection D4 : CTD
Chemical Name ebastine ( From PubChem : EBASTINE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotApprovedNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
469.658 g/mol 0 3 7.1555 False(3/4)
Structure
InChI InChI=1S/C32H39NO2/c1-32(2,3)28-18-16-25(17-19-28)30(34)15-10-22-33-23-20-29(21-24-33)35-31(26-11-6-4-7-12-26)27-13-8-5-9-14-27/h4-9,11-14,16-19,29,31H,10,15,20-24H2,1-3H3
InChIKey MJJALKDDGIKVBE-UHFFFAOYSA-N
Links

Gene (5 / 12)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDincreases(hydroxylation)CYP2J2
C058249
CTDdecreases(methylation)CYP2J2
C058249
CTDdecreases(reaction)CYP2J2
C058249
CTDdecreases(activity)CYP2J2
C058249
CTDdecreases(activity)KCNA5
C058249
PubChem PotencyuM11.886GMNN-GI(Protien) :
PubChem PotencyuM4.645MTOR-GI(Protien) :
PubChem PotencyuM20.749MTOR-GI(Protien) :
PubChem PotencyuM5.957TDP1-GI(Protien) :
PubChem PotencyuM11.886TDP1-GI(Protien) :
ChEMBLPotencynM20749.100MTOR
-Target : CHEMBL2842
ChEMBLPotencynM4645.100MTOR
-Target : CHEMBL2842
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).