Tan Lab | DSigDB

Gene Set: D4 : CTD - norelgestromin

Collection

D4 : CTD

Chemical Name

norelgestromin ( From PubChem : NORELGESTROMIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
327.46 g/mol	2	3	4.1437	True

Structure

InChI

InChI=1S/C21H29NO2/c1-3-20-11-9-17-16-8-6-15(22-24)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23-24H,3,5-12H2,1H3/b22-15+/t16-,17+,18+,19-,20-,21-/m0/s1

InChIKey

ISHXLNHNDMZNMC-VTKCIJPMSA-N

Links

Gene (6 / 17)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			ALB		C449219
CTD	affects(localization)			AR		C057224
CTD	affects(binding)			AR		C057224
CTD	decreases(activity)			AR		C057224
CTD	decreases(expression)			AR		C057224
PubChem	Potency-Replicate_1	uM	0.034	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.425	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.008	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.253	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.832	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	39.048	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	23.710	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.042	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.151	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.425	ESR1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	21.136	TDP1	-	GI(Protien) :

Download gene sets

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