Tan Lab | DSigDB

Gene Set: D4 : CTD - calcipotriene

Collection

D4 : CTD

Chemical Name

calcipotriene ( From PubChem : CALCIPOTRIOL HYDRATE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
412.605 g/mol	3	3	5.0906	False(3/4)

Structure

InChI

InChI=1S/C27H40O3/c1-17(6-13-25(29)20-8-9-20)23-11-12-24-19(5-4-14-27(23,24)3)7-10-21-15-22(28)16-26(30)18(21)2/h6-7,10,13,17,20,22-26,28-30H,2,4-5,8-9,11-12,14-16H2,1,3H3

InChIKey

LWQQLNNNIPYSNX-UHFFFAOYSA-N

Links

Gene (14 / 22)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			BECN1		C055085
CTD	increases(expression)			CYP24A1		C055085
CTD	decreases(expression)			FLG		C055085
CTD	decreases(expression)			IVL		C055085
CTD	decreases(expression)			KRT10		C055085
CTD	decreases(expression)			KRT16		C055085
CTD	decreases(expression)			KRT17		C055085
CTD	affects(binding)			VDR		C055085
CTD	affects(reaction)			VDR		C055085
CTD	affects(response to substance)			VDR		C055085
PubChem	AR Potency (uM)	uM	26.603	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.603	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.314	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	23.014	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	33.489	HSPB1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.660	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	3.758	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	29.847	NR1H4	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
PubChem	Potency	uM	26.609	TDP1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.024	VDR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	13.332	VDR	-	GI(Protien) :

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