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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol

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Collection	D4 : CTD
Chemical Name	3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol ( From PubChem : CP-55940 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 376.573 g/mol 3 3 5.6573 False(3/4)
Structure
InChI	InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1
InChIKey	YNZFFALZMRAPHQ-SYYKKAFVSA-N
Links
Gene (27 / 109) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD affects(binding) ALDOC C054649 CTD increases(activity) ALDOC C054649 CTD increases(expression) ALDOC C054649 CTD affects(binding) BTG2 C054649 CTD increases(activity) BTG2 C054649 CTD increases(expression) BTG2 C054649 CTD affects(binding) CCL2 C054649 CTD increases(activity) CCL2 C054649 CTD increases(expression) CCL2 C054649 CTD increases(expression) CCL2 C054649 CTD increases(reaction) CCL2 C054649 CTD decreases(reaction) CCL2 C054649 CTD affects(binding) CCL4 C054649 CTD increases(activity) CCL4 C054649 CTD increases(expression) CCL4 C054649 CTD affects(binding) CNR1 C054649 CTD increases(activity) CNR1 C054649 CTD affects(binding) CNR1 C054649 CTD increases(abundance) CNR1 C054649 CTD increases(activity) CNR1 C054649 CTD increases(activity) CNR1 C054649 CTD decreases(secretion) CNR1 C054649 CTD affects(reaction) CNR1 C054649 CTD increases(activity) CNR1 C054649 CTD affects(binding) CNR1 C054649 CTD affects(binding) CNR1 C054649 CTD decreases(reaction) CNR1 C054649 CTD increases(abundance) CNR1 C054649 CTD increases(activity) CNR1 C054649 CTD affects(binding) CNR2 C054649 CTD decreases(reaction) CNR2 C054649 CTD affects(binding) CNR2 C054649 CTD increases(activity) CNR2 C054649 CTD affects(binding) CNR2 C054649 CTD decreases(reaction) CNR2 C054649 CTD increases(abundance) CNR2 C054649 CTD increases(activity) CNR2 C054649 CTD affects(binding) CNR2 C054649 CTD increases(activity) CNR2 C054649 CTD increases(expression) CNR2 C054649 CTD affects(binding) CNR2 C054649 CTD increases(activity) CNR2 C054649 CTD decreases(secretion) CNR2 C054649 CTD increases(expression) CNR2 C054649 CTD increases(reaction) CNR2 C054649 CTD affects(binding) CNR2 C054649 CTD decreases(reaction) CNR2 C054649 CTD decreases(reaction) CNR2 C054649 CTD increases(expression) CXCL8 C054649 CTD affects(binding) CXCL8 C054649 CTD increases(activity) CXCL8 C054649 CTD increases(expression) CXCL8 C054649 CTD affects(expression) CXCL8 C054649 CTD decreases(reaction) CXCL8 C054649 CTD decreases(secretion) CXCL8 C054649 CTD increases(activity) CXCL8 C054649 CTD increases(expression) CXCL8 C054649 CTD increases(reaction) CXCL8 C054649 CTD decreases(reaction) CXCL8 C054649 CTD affects(binding) GNA13 C054649 CTD affects(reaction) GNA13 C054649 CTD increases(activity) GNA13 C054649 CTD affects(binding) GPR55 C054649 CTD increases(activity) GPR55 C054649 CTD affects(reaction) GPR55 C054649 CTD affects(binding) JUNB C054649 CTD increases(activity) JUNB C054649 CTD increases(expression) JUNB C054649 CTD affects(cotreatment) MAPK1 C054649 CTD increases(activity) MAPK1 C054649 CTD increases(reaction) MAPK1 C054649 CTD increases(phosphorylation) MAPK1 C054649 CTD affects(reaction) MAPK1 C054649 CTD decreases(reaction) MAPK1 C054649 CTD affects(cotreatment) MAPK3 C054649 CTD increases(activity) MAPK3 C054649 CTD increases(reaction) MAPK3 C054649 CTD increases(phosphorylation) MAPK3 C054649 CTD affects(reaction) MAPK3 C054649 CTD decreases(reaction) MAPK3 C054649 CTD affects(binding) NFKBIA C054649 CTD increases(activity) NFKBIA C054649 CTD increases(expression) NFKBIA C054649 CTD affects(binding) TNF C054649 CTD increases(activity) TNF C054649 CTD increases(expression) TNF C054649 CTD affects(expression) TNF C054649 CTD decreases(reaction) TNF C054649 PubChem None uM ADAM10 - GI(Protien) : PubChem Potency uM 16.354 ATAD5 - GI(Protien) : PubChem Potency uM 10.000 ATXN2 - GI(Protien) : PubChem Potency uM 25.119 CYP2C9 - GI(Protien) : PubChem None uM DRD3 - GI(Protien) : PubChem None uM DRD3 - GI(Protien) : PubChem Potency uM 2.593 IDH1 - GI(Protien) : PubChem None uM IL1B - GI(Protien) : PubChem Potency uM 8.912 KCNH2 GI(Protien) : PubChem Potency uM 8.912 KCNH2 GI(Protien) : PubChem None uM KCNK3 - GI(Protien) : PubChem None uM OPRM1 - GI(Protien) : PubChem None uM PPP5C - GI(Protien) : PubChem Potency uM 12.589 SMAD3 - GI(Protien) : PubChem Potency uM 18.356 TDP1 - GI(Protien) : PubChem Potency uM 20.596 TDP1 - GI(Protien) : ChEMBL Potency nM 16353.500 ATAD5 - Target : CHEMBL1741209 ChEMBL Activity - CNR1 - Target : CHEMBL218 ChEMBL Activity - CNR1 - Target : CHEMBL218 ChEMBL Activity - CNR2 - Target : CHEMBL253 ChEMBL Potency nM 25118.900 CYP2C9 - Target : CHEMBL3397
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