Tan Lab | DSigDB

Gene Set: D4 : CTD - garcinol

Collection

D4 : CTD

Chemical Name

garcinol ( From PubChem : GARCINOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
602.8 g/mol	3	6	8.758	False(2/4)

Structure

InChI

InChI=1S/C38H50O6/c1-22(2)11-13-27(25(7)8)20-37-21-28(15-12-23(3)4)36(9,10)38(35(37)44,18-17-24(5)6)34(43)31(33(37)42)32(41)26-14-16-29(39)30(40)19-26/h11-12,14,16-17,19,27-28,39-41H,7,13,15,18,20-21H2,1-6,8-10H3/b32-31-/t27-,28+,37+,38-/m0/s1

InChIKey

DTTONLKLWRTCAB-BZSUNBQASA-N

Links

Gene (22 / 48)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	decreases(activity)		AKT1		C054597
CTD	decreases(phosphorylation)		AKT1		C054597
CTD	decreases(expression)		BCL2		C054597
CTD	increases(cleavage)		BID		C054597
CTD	increases(activity)		CASP3		C054597
CTD	increases(cleavage)		CASP3		C054597
CTD	increases(cleavage)		CASP9		C054597
CTD	decreases(reaction)		CCL2		C054597
CTD	increases(expression)		CCL2		C054597
CTD	increases(reaction)		CCL2		C054597
CTD	decreases(expression)		CCL2		C054597
CTD	affects(localization)		CYCS		C054597
CTD	affects(binding)		EP300		C054597
CTD	decreases(reaction)		EP300		C054597
CTD	increases(reaction)		EP300		C054597
CTD	decreases(reaction)		ICAM1		C054597
CTD	increases(expression)		ICAM1		C054597
CTD	increases(reaction)		ICAM1		C054597
CTD	affects(binding)		IL1B		C054597
CTD	decreases(reaction)		IL1B		C054597
CTD	increases(reaction)		IL1B		C054597
CTD	increases(expression)		IL1B		C054597
CTD	decreases(reaction)		IL6		C054597
CTD	increases(expression)		IL6		C054597
CTD	decreases(activity)		MAPK1		C054597
CTD	decreases(phosphorylation)		MAPK1		C054597
CTD	decreases(activity)		MAPK3		C054597
CTD	decreases(phosphorylation)		MAPK3		C054597
CTD	decreases(expression)		MMP7		C054597
CTD	increases(cleavage)		PARP1		C054597
CTD	decreases(activity)		PIK3R1		C054597
CTD	decreases(phosphorylation)		PIK3R1		C054597
CTD	decreases(phosphorylation)		PTK2		C054597
CTD	affects(binding)		RELA		C054597
CTD	decreases(reaction)		RELA		C054597
CTD	increases(reaction)		RELA		C054597
CTD	decreases(activity)		SRC		C054597
CTD	decreases(phosphorylation)		SRC		C054597
CTD	decreases(reaction)		TNF		C054597
CTD	increases(expression)		TNF		C054597
CTD	increases(reaction)		TNF		C054597
CTD	decreases(reaction)		TNF		C054597
CTD	increases(expression)		TNF		C054597
CTD	increases(reaction)		TNF		C054597
CTD	decreases(reaction)		VCAM1		C054597
CTD	increases(expression)		VCAM1		C054597
ChEMBL	Activity	-	EP300	-	Target : CHEMBL3784
ChEMBL	Inhibition	-	STAT1	-	Target : CHEMBL6101

Download gene sets

gmt, text, Detailed text