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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - mometasone furoate

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Collection	D4 : CTD
Chemical Name	mometasone furoate ( From PubChem : MOMETASONE FUROATE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Not Approved Approved Approved Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 521.43 g/mol 1 6 4.8692 False(3/4)
Structure
InChI	InChI=1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1
InChIKey	WOFMFGQZHJDGCX-ZULDAHANSA-N
Links
Gene (19 / 39) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(reaction) ABCB1 C053915 CTD decreases(response to substance) ABCB1 C053915 CTD increases(export) ABCB1 C053915 CTD decreases(reaction) ABCG2 C053915 CTD increases(export) ABCG2 C053915 CTD increases(activity) ABCG2 C053915 CTD decreases(reaction) CSF2 C053915 CTD increases(secretion) CSF2 C053915 CTD decreases(activity) CYP2C8 C053915 CTD decreases(secretion) IL10 C053915 CTD decreases(reaction) IL1B C053915 CTD increases(secretion) IL1B C053915 CTD affects(binding) PGR C053915 CTD increases(activity) PGR C053915 CTD decreases(reaction) TNF C053915 CTD increases(expression) TNF C053915 CTD decreases(secretion) TNF C053915 CTD decreases(reaction) VCAM1 C053915 CTD increases(expression) VCAM1 C053915 PubChem Potency-Replicate_1 uM 0.001 AR - GI(Protien) : PubChem Ratio Potency (uM) uM 5.741 AR - GI(Protien) : PubChem None uM CFTR - GI(Protien) : PubChem Potency-Replicate_1 uM 29.847 HSPB1 - GI(Protien) : PubChem Potency uM 8.912 IDH1 - GI(Protien) : PubChem Potency uM 16.360 IDH1 - GI(Protien) : PubChem Potency uM 35.481 IDH1 - GI(Protien) : PubChem None uM IL1B - GI(Protien) : PubChem Potency-Replicate_1 uM 13.332 NFE2L2 - GI(Protien) : PubChem Ratio Potency (uM) uM 17.779 NFE2L2 - GI(Protien) : PubChem Potency-Replicate_1 uM 26.601 NR1H4 - GI(Protien) : PubChem Ratio Potency (uM) uM 26.601 NR1H4 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.000 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.000 NR3C1 - GI(Protien) : PubChem None uM PPP1CA - GI(Protien) : PubChem None uM PPP1CA - GI(Protien) : PubChem None uM STK33 - GI(Protien) : PubChem Potency uM 11.582 TDP1 - GI(Protien) : PubChem Potency uM 12.762 TDP1 - GI(Protien) : PubChem Potency uM 16.360 TDP1 - GI(Protien) :
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