DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

Home

Search Gene

Collection

Browse

Download

Help

DSigDB Home

Search Gene

Collections

Browse Gene Sets

Download

Help

Gene Set: D4 : CTD - 6-isopropoxy-9-oxoxanthene-2-carboxylic acid

---

Collection	D4 : CTD
Chemical Name	6-isopropoxy-9-oxoxanthene-2-carboxylic acid ( From PubChem : AH 6809 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 298.29 g/mol 1 5 3.4316 True
Structure
InChI	InChI=1S/C17H14O5/c1-9(2)21-11-4-5-12-15(8-11)22-14-6-3-10(17(19)20)7-13(14)16(12)18/h3-9H,1-2H3,(H,19,20)
InChIKey	AQFFXPQJLZFABJ-UHFFFAOYSA-N
Links
Gene (33 / 102) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD affects(binding) AKT1 C053876 CTD affects(cotreatment) AKT1 C053876 CTD decreases(reaction) AKT1 C053876 CTD decreases(phosphorylation) AKT1 C053876 CTD affects(binding) ARRB1 C053876 CTD affects(cotreatment) ARRB1 C053876 CTD decreases(reaction) ARRB1 C053876 CTD decreases(phosphorylation) ARRB1 C053876 CTD affects(binding) AXIN1 C053876 CTD affects(cotreatment) AXIN1 C053876 CTD increases(reaction) AXIN1 C053876 CTD affects(binding) BAD C053876 CTD affects(cotreatment) BAD C053876 CTD increases(reaction) BAD C053876 CTD decreases(phosphorylation) BAD C053876 CTD affects(binding) BAX C053876 CTD affects(cotreatment) BAX C053876 CTD increases(reaction) BAX C053876 CTD increases(expression) BAX C053876 CTD affects(binding) BCL2 C053876 CTD affects(cotreatment) BCL2 C053876 CTD increases(reaction) BCL2 C053876 CTD decreases(expression) BCL2 C053876 CTD affects(binding) BCL2L1 C053876 CTD affects(cotreatment) BCL2L1 C053876 CTD increases(reaction) BCL2L1 C053876 CTD decreases(expression) BCL2L1 C053876 CTD affects(cotreatment) CASP3 C053876 CTD increases(activity) CASP3 C053876 CTD increases(cleavage) CASP3 C053876 CTD affects(binding) CTNNB1 C053876 CTD affects(cotreatment) CTNNB1 C053876 CTD increases(reaction) CTNNB1 C053876 CTD increases(degradation) CTNNB1 C053876 CTD decreases(reaction) CYP19A1 C053876 CTD increases(expression) CYP19A1 C053876 CTD decreases(reaction) CYP1B1 C053876 CTD increases(expression) CYP1B1 C053876 CTD affects(binding) EGFR C053876 CTD affects(cotreatment) EGFR C053876 CTD decreases(reaction) EGFR C053876 CTD decreases(expression) EGFR C053876 CTD decreases(phosphorylation) EGFR C053876 CTD affects(cotreatment) EGR1 C053876 CTD decreases(expression) EGR1 C053876 CTD affects(cotreatment) FOS C053876 CTD decreases(expression) FOS C053876 CTD affects(binding) GSK3B C053876 CTD affects(cotreatment) GSK3B C053876 CTD decreases(reaction) GSK3B C053876 CTD increases(reaction) GSK3B C053876 CTD decreases(phosphorylation) GSK3B C053876 CTD decreases(reaction) HSD11B1 C053876 CTD increases(activity) HSD11B1 C053876 CTD affects(binding) IL1R1 C053876 CTD affects(cotreatment) IL1R1 C053876 CTD decreases(reaction) IL1R1 C053876 CTD decreases(expression) IL1R1 C053876 CTD affects(cotreatment) JUN C053876 CTD decreases(phosphorylation) JUN C053876 CTD affects(binding) MAPK1 C053876 CTD affects(cotreatment) MAPK1 C053876 CTD decreases(reaction) MAPK1 C053876 CTD decreases(phosphorylation) MAPK1 C053876 CTD affects(binding) MAPK3 C053876 CTD affects(cotreatment) MAPK3 C053876 CTD decreases(reaction) MAPK3 C053876 CTD decreases(phosphorylation) MAPK3 C053876 CTD affects(cotreatment) MYC C053876 CTD decreases(phosphorylation) MYC C053876 CTD affects(cotreatment) NFKB1 C053876 CTD decreases(expression) NFKB1 C053876 CTD affects(cotreatment) NFKBIA C053876 CTD decreases(phosphorylation) NFKBIA C053876 CTD affects(cotreatment) PARP1 C053876 CTD increases(activity) PARP1 C053876 CTD increases(cleavage) PARP1 C053876 CTD affects(binding) PTGER2 C053876 CTD affects(cotreatment) PTGER2 C053876 CTD decreases(reaction) PTGER2 C053876 CTD affects(binding) PTGER4 C053876 CTD affects(cotreatment) PTGER4 C053876 CTD decreases(reaction) PTGER4 C053876 CTD decreases(reaction) PTGS2 C053876 CTD increases(expression) PTGS2 C053876 CTD affects(cotreatment) RELA C053876 CTD decreases(expression) RELA C053876 CTD decreases(phosphorylation) RELA C053876 CTD affects(cotreatment) SP1 C053876 CTD decreases(expression) SP1 C053876 CTD affects(binding) SRC C053876 CTD affects(cotreatment) SRC C053876 CTD decreases(reaction) SRC C053876 CTD decreases(phosphorylation) SRC C053876 CTD affects(cotreatment) TCF7 C053876 CTD decreases(expression) TCF7 C053876 CTD affects(cotreatment) TCF7L2 C053876 CTD decreases(expression) TCF7L2 C053876 CTD affects(binding) TNFRSF1A C053876 CTD affects(cotreatment) TNFRSF1A C053876 CTD decreases(reaction) TNFRSF1A C053876 CTD decreases(expression) TNFRSF1A C053876
Download gene sets	gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).