Tan Lab | DSigDB

Gene Set: D4 : CTD - triflumizol

Collection

D4 : CTD

Chemical Name

triflumizol ( From PubChem : TRIFLUMIZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
345.747 g/mol	0	4	4.5602	True

Structure

InChI

InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3/b21-14+

InChIKey

Links

Gene (12 / 31)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			ADIPOQ		C053549
CTD	increases(expression)			ADIPOQ		C053549
CTD	decreases(reaction)			AR		C053549
CTD	increases(activity)			AR		C053549
CTD	affects(cotreatment)			CIDEC		C053549
CTD	increases(expression)			CIDEC		C053549
CTD	affects(cotreatment)			FABP4		C053549
CTD	decreases(reaction)			FABP4		C053549
CTD	increases(expression)			FABP4		C053549
CTD	affects(cotreatment)			INS		C053549
CTD	decreases(reaction)			INS		C053549
CTD	increases(expression)			INS		C053549
CTD	affects(cotreatment)			LEP		C053549
CTD	decreases(reaction)			LEP		C053549
CTD	increases(expression)			LEP		C053549
CTD	affects(cotreatment)			LPL		C053549
CTD	decreases(reaction)			LPL		C053549
CTD	increases(expression)			LPL		C053549
CTD	affects(binding)			NR1I2		C053549
CTD	increases(activity)			NR1I2		C053549
CTD	increases(activity)			PPARG		C053549
PubChem	Potency-Replicate_1	uM	21.668	AR	-	GI(Protien) :
PubChem	Potency	uM	44.668	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.015	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	3.180	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	19.331	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.131	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	35.481	NR1I2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	30.881	PPARG	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	34.648	VDR	-	GI(Protien) :

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