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Gene Set: D4 : CTD - oxybutynin

Collection D4 : CTD
Chemical Name oxybutynin ( From PubChem : OXYBUTYNIN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedApprovedNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
357.486 g/mol 1 4 3.3429 True
Structure
InChI InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3/t22-/m1/s1
InChIKey XIQVNETUBQGFHX-JOCHJYFZSA-N
Links

Gene (8 / 12)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(activity)ABCB11
C005419
CTDincreases(hydrolysis)CES2
C005419
CTDaffects(binding)CHRM2
C005419
CTDdecreases(activity)CHRM2
C005419
CTDaffects(binding)CHRM3
C005419
CTDdecreases(activity)CHRM3
C005419
CTDdecreases(activity)CYP2C8
C005419
CTDdecreases(reaction)SLC22A2
C005419
CTDincreases(uptake)SLC22A2
C005419
ChEMBLInhibition-CYP2D6
-Target : CHEMBL289
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
ChEMBLInhibition-CYP3A4
-Target : CHEMBL340
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