Tan Lab | DSigDB

Gene Set: D4 : CTD - nebivolol

Collection

D4 : CTD

Chemical Name

nebivolol ( From PubChem : NEBIVOLOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
405.435 g/mol	3	5	2.7545	True

Structure

InChI

InChI=1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2/t17-,18-,21-,22-/m1/s1

InChIKey

KOHIRBRYDXPAMZ-MCEIDBOGSA-N

Links

Gene (18 / 23)

⊖ Less

Source	Type	Gene	Other
CTD	affects(binding)	ADRB1	C052753
CTD	decreases(reaction)	ADRB1	C052753
CTD	decreases(expression)	CCL2	C052753
CTD	decreases(secretion)	CCL2	C052753
CTD	decreases(reaction)	DDAH2	C052753
CTD	increases(expression)	DDAH2	C052753
CTD	increases(activity)	DDAH2	C052753
CTD	increases(expression)	DHCR24	C052753
CTD	decreases(expression)	EDN1	C052753
CTD	decreases(secretion)	EDN1	C052753
CTD	affects(activity)	ESR2	C052753
CTD	decreases(expression)	ICAM1	C052753
CTD	decreases(expression)	IL1A	C052753
CTD	increases(activity)	NOS3	C052753
CTD	increases(expression)	NPPB	C052753
CTD	decreases(expression)	PDGFA	C052753
CTD	decreases(expression)	PDGFB	C052753
CTD	decreases(expression)	PTGS2	C052753
CTD	decreases(expression)	SELE	C052753
CTD	decreases(expression)	SELP	C052753
CTD	decreases(expression)	TNFAIP6	C052753
CTD	decreases(expression)	VCAM1	C052753
CTD	increases(expression)	VIPR1	C052753

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