Tan Lab | DSigDB

Gene Set: D4 : CTD - pararosaniline

Collection

D4 : CTD

Chemical Name

pararosaniline ( From PubChem : PARAROSANILINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
287.358 g/mol	3	3	5.0608	False(3/4)

Structure

InChI

InChI=1S/C19H17N3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,20H,21-22H2

InChIKey

AFAIELJLZYUNPW-UHFFFAOYSA-N

Links

Gene (29 / 44)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			BCHE		C005409
CTD	decreases(reaction)			GSTP1		C005409
CTD	increases(metabolic processing)			GSTP1		C005409
CTD	decreases(activity)			NR3C1		C005409
CTD	decreases(expression)			NR3C1		C005409
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	Average IC50	uM	3.430	APOBEC3G	-	GI(Protien) :
PubChem	Potency	uM	28.184	ATXN2	-	GI(Protien) :
PubChem	None	uM		CCR6	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	1.585	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	3.162	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	1.585	HIF1A	-	GI(Protien) :
PubChem	None	uM		HNF4A	-	GI(Protien) :
PubChem	None	uM		HTR5A	-	GI(Protien) :
PubChem	Potency	uM	23.109	IDH1	-	GI(Protien) :
PubChem	Potency	uM	1.630	MAPT	-	GI(Protien) :
PubChem	2nd Test Concentration	uM	6.400	MAPT	-	GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	AC50_uM	uM	6.080	MLLT3	-	GI(Protien) :
PubChem	None	uM		MLLT3	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	Potency	uM	7.308	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		PLA2G3	-	GI(Protien) :
PubChem	None	uM		PLIN5	-	GI(Protien) :
PubChem	None	uM		PLIN5	-	GI(Protien) :
PubChem	IC50	uM	98.010	RACGAP1	-	GI(Protien) :
PubChem	None	uM		SELE	-	GI(Protien) :
PubChem	Potency	uM	2.323	SNCA	-	GI(Protien) :
PubChem	Potency	uM	2.909	TDP1	-	GI(Protien) :
PubChem	Potency	uM	3.264	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	510.000	APP	-	Target : CHEMBL2487
ChEMBL	Potency	nM	1584.900	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	3162.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	1584.900	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	7079.500	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	1630.000	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	7307.800	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	2322.740	SNCA	-	Target : CHEMBL6152

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