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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole

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Collection	D4 : CTD
Chemical Name	6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole ( From PubChem : SKF 86002 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 297.35 g/mol 0 4 3.8569 True
Structure
InChI	InChI=1S/C16H12FN3S/c17-13-3-1-11(2-4-13)14-15(12-5-7-18-8-6-12)20-9-10-21-16(20)19-14/h1-8H,9-10H2
InChIKey	YOELZIQOLWZLQC-UHFFFAOYSA-N
Links
Gene (5 / 8) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(expression) MAPK14 C052026 CTD decreases(phosphorylation) MAPK14 C052026 CTD decreases(reaction) PTGS2 C052026 CTD increases(expression) PTGS2 C052026 CTD decreases(expression) TNF C052026 CTD decreases(expression) TOP2A C052026 CTD decreases(phosphorylation) TOP2A C052026 PubChem Potency uM 0.519 YES1 GI(Protien) :
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