Tan Lab | DSigDB

Gene Set: D4 : CTD - demethoxycurcumin

Collection

D4 : CTD

Chemical Name

demethoxycurcumin ( From PubChem : CURCUMIN II )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
338.354 g/mol	2	5	3.3613	True

Structure

InChI

InChI=1S/C20H18O5/c1-25-20-12-15(6-11-19(20)24)5-10-18(23)13-17(22)9-4-14-2-7-16(21)8-3-14/h2-12,21,24H,13H2,1H3/b9-4+,10-5+

InChIKey

Links

Gene (17 / 22)

⊖ Less

Source	Type	Gene	Other
CTD	decreases(activity)	ABCC1	C050229
CTD	decreases(activity)	ABCC2	C050229
CTD	affects(binding)	APP	C050229
CTD	decreases(reaction)	APP	C050229
CTD	decreases(secretion)	APP	C050229
CTD	decreases(reaction)	CASP3	C050229
CTD	increases(activity)	CASP3	C050229
CTD	increases(expression)	GCLM	C050229
CTD	increases(expression)	HMOX1	C050229
CTD	increases(secretion)	INS	C050229
CTD	affects(expression)	KDR	C050229
CTD	decreases(expression)	MMP14	C050229
CTD	decreases(activity)	MMP2	C050229
CTD	decreases(secretion)	MMP2	C050229
CTD	decreases(activity)	MMP9	C050229
CTD	decreases(secretion)	MMP9	C050229
CTD	increases(expression)	NQO1	C050229
CTD	decreases(secretion)	PLAU	C050229
CTD	affects(binding)	PPARG	C050229
CTD	decreases(expression)	TIMP2	C050229
CTD	affects(expression)	VEGFA	C050229
CTD	decreases(expression)	WT1	C050229

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