Tan Lab | DSigDB

Gene Set: D4 : CTD - staurosporine aglycone

Collection

D4 : CTD

Chemical Name

staurosporine aglycone ( From PubChem : K-252A )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
467.473 g/mol	2	8	3.9839	True

Structure

InChI

InChI=1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18-,26+,27+/m1/s1

InChIKey

KOZFSFOOLUUIGY-SOLYNIJKSA-N

Links

Gene (8 / 25)

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Source	Type	Gene	Other
CTD	decreases(reaction)	AKT1	C049985
CTD	increases(phosphorylation)	AKT1	C049985
CTD	affects(binding)	BDNF	C049985
CTD	decreases(activity)	BDNF	C049985
CTD	decreases(expression)	BDNF	C049985
CTD	decreases(reaction)	BDNF	C049985
CTD	affects(cotreatment)	BDNF	C049985
CTD	decreases(reaction)	BDNF	C049985
CTD	increases(phosphorylation)	BDNF	C049985
CTD	affects(binding)	CHRM1	C049985
CTD	increases(reaction)	CHRM1	C049985
CTD	decreases(reaction)	CREB1	C049985
CTD	increases(phosphorylation)	CREB1	C049985
CTD	decreases(reaction)	FOS	C049985
CTD	increases(expression)	FOS	C049985
CTD	decreases(reaction)	MT3	C049985
CTD	decreases(response to substance)	MT3	C049985
CTD	affects(binding)	NTRK2	C049985
CTD	decreases(activity)	NTRK2	C049985
CTD	decreases(expression)	NTRK2	C049985
CTD	decreases(reaction)	NTRK2	C049985
CTD	affects(cotreatment)	NTRK2	C049985
CTD	decreases(response to substance)	NTRK2	C049985
CTD	decreases(reaction)	TNFSF10	C049985
CTD	increases(expression)	TNFSF10	C049985

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