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Gene Set: D4 : CTD - 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

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Collection	D4 : CTD
Chemical Name	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine ( From PubChem : PHIP )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 224.261 g/mol 1 4 2.7987 True
Structure
InChI	InChI=1S/C13H12N4/c1-17-11-7-10(9-5-3-2-4-6-9)8-15-12(11)16-13(17)14/h2-8H,1H3,(H2,14,15,16)
InChIKey	UQVKZNNCIHJZLS-UHFFFAOYSA-N
Links
Gene (179 / 329) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(expression) ABCC1 C049584 CTD increases(expression) ABCC2 C049584 CTD increases(transport) ABCC2 C049584 CTD affects(transport) ABCC2 C049584 CTD decreases(activity) ABCC2 C049584 CTD decreases(expression) ABCG2 C049584 CTD increases(expression) ABCG2 C049584 CTD decreases(activity) ABCG2 C049584 CTD increases(transport) ABCG2 C049584 CTD decreases(transport) ABCG2 C049584 CTD affects(transport) ABCG2 C049584 CTD decreases(transport) ABCG2 C049584 CTD increases(secretion) ABCG2 C049584 CTD increases(transport) ABCG2 C049584 CTD decreases(reaction) ABCG2 C049584 CTD decreases(reaction) ABCG2 C049584 CTD decreases(activity) AHR C049584 CTD decreases(response to substance) AHR C049584 CTD decreases(reaction) AHR C049584 CTD increases(expression) AHR C049584 CTD affects(response to substance) AHR C049584 CTD affects(response to substance) AHRR C049584 CTD increases(expression) AKAP12 C049584 CTD increases(expression) ALDH3A1 C049584 CTD decreases(expression) ALOX5 C049584 CTD decreases(expression) APAF1 C049584 CTD increases(expression) ATF4 C049584 CTD increases(expression) ATF7IP C049584 CTD increases(expression) ATL1 C049584 CTD increases(expression) BAX C049584 CTD increases(expression) BAX C049584 CTD increases(expression) BAX C049584 CTD increases(reaction) BAX C049584 CTD decreases(expression) BCAS3 C049584 CTD increases(expression) BCL2 C049584 CTD increases(expression) BCL2 C049584 CTD decreases(expression) BNC2 C049584 CTD increases(expression) BUB1 C049584 CTD increases(expression) BUB1B C049584 CTD decreases(expression) C1QTNF3 C049584 CTD decreases(expression) CAB39L C049584 CTD increases(activity) CASP3 C049584 CTD affects(cotreatment) CASP3 C049584 CTD decreases(expression) CASP8 C049584 CTD decreases(expression) CCNA2 C049584 CTD increases(expression) CCNA2 C049584 CTD increases(expression) CCNB1 C049584 CTD increases(expression) CD27 C049584 CTD increases(expression) CDC25C C049584 CTD increases(expression) CDC34 C049584 CTD increases(expression) CDC45 C049584 CTD decreases(expression) CDH1 C049584 CTD decreases(reaction) CDH1 C049584 CTD decreases(expression) CDH26 C049584 CTD decreases(expression) CDK1 C049584 CTD increases(expression) CDK13 C049584 CTD decreases(expression) CDK9 C049584 CTD increases(expression) CDKN1A C049584 CTD increases(expression) CDKN1A C049584 CTD increases(phosphorylation) CEBPB C049584 CTD affects(response to substance) CEBPB C049584 CTD increases(expression) CENPF C049584 CTD increases(expression) CEP290 C049584 CTD decreases(expression) CFHR4 C049584 CTD increases(expression) CHAT C049584 CTD decreases(expression) CLDN14 C049584 CTD increases(expression) CTSD C049584 CTD increases(expression) CXCR3 C049584 CTD increases(activity) CYP1A1 C049584 CTD increases(expression) CYP1A1 C049584 CTD affects(cotreatment) CYP1A1 C049584 CTD increases(expression) CYP1A1 C049584 CTD decreases(reaction) CYP1A1 C049584 CTD increases(expression) CYP1A1 C049584 CTD increases(metabolic processing) CYP1A1 C049584 CTD increases(chemical synthesis) CYP1A1 C049584 CTD increases(activity) CYP1A1 C049584 CTD affects(cotreatment) CYP1A1 C049584 CTD increases(hydroxylation) CYP1A1 C049584 CTD increases(chemical synthesis) CYP1A1 C049584 CTD increases(expression) CYP1A1 C049584 CTD increases(reaction) CYP1A1 C049584 CTD affects(cotreatment) CYP1A2 C049584 CTD increases(expression) CYP1A2 C049584 CTD affects(cotreatment) CYP1A2 C049584 CTD increases(mutagenesis) CYP1A2 C049584 CTD decreases(ethylation) CYP1A2 C049584 CTD decreases(reaction) CYP1A2 C049584 CTD increases(expression) CYP1A2 C049584 CTD decreases(reaction) CYP1A2 C049584 CTD increases(expression) CYP1A2 C049584 CTD affects(cotreatment) CYP1A2 C049584 CTD increases(hydroxylation) CYP1A2 C049584 CTD increases(chemical synthesis) CYP1A2 C049584 CTD affects(cotreatment) CYP1A2 C049584 CTD increases(response to substance) CYP1A2 C049584 CTD increases(activity) CYP1A2 C049584 CTD increases(activity) CYP1A2 C049584 CTD increases(hydroxylation) CYP1A2 C049584 CTD increases(activity) CYP1A2 C049584 CTD increases(hydroxylation) CYP1A2 C049584 CTD increases(hydroxylation) CYP1A2 C049584 CTD increases(metabolic processing) CYP1A2 C049584 CTD increases(metabolic processing) CYP1A2 C049584 CTD increases(chemical synthesis) CYP1A2 C049584 CTD increases(chemical synthesis) CYP1A2 C049584 CTD increases(metabolic processing) CYP1A2 C049584 CTD increases(activity) CYP1A2 C049584 CTD increases(metabolic processing) CYP1A2 C049584 CTD increases(activity) CYP1A2 C049584 CTD increases(oxidation) CYP1A2 C049584 CTD increases(activity) CYP1A2 C049584 CTD increases(oxidation) CYP1A2 C049584 CTD increases(hydroxylation) CYP1A2 C049584 CTD affects(cotreatment) CYP1B1 C049584 CTD increases(expression) CYP1B1 C049584 CTD decreases(expression) CYP1B1 C049584 CTD increases(activity) CYP1B1 C049584 CTD increases(expression) CYP1B1 C049584 CTD increases(metabolic processing) CYP1B1 C049584 CTD increases(chemical synthesis) CYP1B1 C049584 CTD decreases(expression) CYP27B1 C049584 CTD increases(metabolic processing) CYP2C19 C049584 CTD increases(chemical synthesis) CYP2C19 C049584 CTD increases(metabolic processing) CYP2D6 C049584 CTD increases(chemical synthesis) CYP2D6 C049584 CTD decreases(expression) CYTB C049584 CTD decreases(activity) DDC C049584 CTD decreases(expression) DHRS2 C049584 CTD increases(expression) DIAPH3 C049584 CTD decreases(expression) DIDO1 C049584 CTD increases(expression) DNAJB8 C049584 CTD decreases(expression) EGF C049584 CTD increases(expression) EGR1 C049584 CTD affects(response to substance) EPS8L3 C049584 CTD decreases(expression) ERCC1 C049584 CTD affects(binding) ESR1 C049584 CTD increases(activity) ESR1 C049584 CTD decreases(reaction) ESR1 C049584 CTD increases(activity) ESR1 C049584 CTD affects(response to substance) ESR1 C049584 CTD decreases(reaction) ESR1 C049584 CTD decreases(expression) ESR1 C049584 CTD decreases(response to substance) ESR1 C049584 CTD decreases(expression) F2R C049584 CTD decreases(expression) FHIT C049584 CTD increases(expression) FNBP1L C049584 CTD increases(expression) FOS C049584 CTD increases(expression) GAB1 C049584 CTD increases(expression) GADD45A C049584 CTD decreases(expression) GNA13 C049584 CTD increases(expression) GNAT1 C049584 CTD decreases(expression) GNMT C049584 CTD decreases(expression) GOLGA8A C049584 CTD decreases(expression) GPR135 C049584 CTD decreases(expression) GRM3 C049584 CTD increases(expression) GRM4 C049584 CTD decreases(expression) GSTA1 C049584 CTD affects(response to substance) GSTA1 C049584 CTD affects(cotreatment) GSTA1 C049584 CTD increases(expression) GSTA1 C049584 CTD affects(response to substance) GSTM1 C049584 CTD affects(response to substance) GSTP1 C049584 CTD affects(response to substance) GSTT1 C049584 CTD affects(response to substance) HBB C049584 CTD decreases(reaction) HBB C049584 CTD increases(response to substance) HBB C049584 CTD decreases(expression) HCCS C049584 CTD decreases(expression) HEMK1 C049584 CTD increases(expression) HIF1A C049584 CTD affects(cotreatment) HIST3H3 C049584 CTD decreases(methylation) HIST3H3 C049584 CTD affects(cotreatment) HMOX1 C049584 CTD increases(expression) HMOX1 C049584 CTD decreases(expression) HNF1B C049584 CTD affects(cotreatment) HPRT1 C049584 CTD increases(mutagenesis) HPRT1 C049584 CTD increases(abundance) HPRT1 C049584 CTD increases(mutagenesis) HPRT1 C049584 CTD increases(mutagenesis) HPRT1 C049584 CTD affects(splicing) HPRT1 C049584 CTD increases(mutagenesis) HPRT1 C049584 CTD increases(expression) HRAS C049584 CTD increases(mutagenesis) HRAS C049584 CTD affects(reaction) HRAS C049584 CTD increases(abundance) HRAS C049584 CTD increases(phosphorylation) HRAS C049584 CTD affects(response to substance) HRAS C049584 CTD decreases(expression) HSFX1 C049584 CTD increases(expression) IFNG C049584 CTD decreases(expression) IL1B C049584 CTD increases(expression) IL6 C049584 CTD increases(expression) KAT6B C049584 CTD increases(expression) KCTD2 C049584 CTD affects(cotreatment) KDM1A C049584 CTD affects(localization) KDM1A C049584 CTD increases(expression) KDM1A C049584 CTD decreases(expression) LCN15 C049584 CTD decreases(expression) LRRIQ3 C049584 CTD increases(phosphorylation) MAP2K1 C049584 CTD increases(phosphorylation) MAP2K2 C049584 CTD increases(expression) MAPK1 C049584 CTD increases(phosphorylation) MAPK1 C049584 CTD decreases(reaction) MAPK1 C049584 CTD affects(reaction) MAPK1 C049584 CTD increases(phosphorylation) MAPK1 C049584 CTD decreases(reaction) MAPK1 C049584 CTD affects(expression) MAPK14 C049584 CTD increases(expression) MAPK3 C049584 CTD increases(phosphorylation) MAPK3 C049584 CTD decreases(reaction) MAPK3 C049584 CTD affects(reaction) MAPK3 C049584 CTD increases(phosphorylation) MAPK3 C049584 CTD decreases(reaction) MAPK3 C049584 CTD decreases(expression) MAT2A C049584 CTD increases(expression) MCM2 C049584 CTD increases(expression) MCM6 C049584 CTD increases(expression) MCM7 C049584 CTD increases(expression) MCM8 C049584 CTD increases(expression) MDM2 C049584 CTD affects(response to substance) MLH1 C049584 CTD increases(expression) MMP2 C049584 CTD decreases(reaction) MMP2 C049584 CTD increases(expression) MMP9 C049584 CTD increases(secretion) MMP9 C049584 CTD decreases(reaction) MMP9 C049584 CTD affects(response to substance) MSH6 C049584 CTD increases(expression) MYC C049584 CTD decreases(expression) N4BP1 C049584 CTD affects(response to substance) NAT1 C049584 CTD decreases(expression) NAT2 C049584 CTD increases(activity) NAT2 C049584 CTD increases(expression) NAV2 C049584 CTD increases(expression) NEK2 C049584 CTD increases(expression) NFE2L2 C049584 CTD affects(cotreatment) NFE2L2 C049584 CTD increases(expression) NKG7 C049584 CTD increases(expression) NME9 C049584 CTD increases(expression) NOX1 C049584 CTD decreases(activity) NOX1 C049584 CTD decreases(reaction) NOX1 C049584 CTD increases(abundance) NOX1 C049584 CTD decreases(response to substance) NOX1 C049584 CTD affects(reaction) NOX1 C049584 CTD affects(response to substance) NOX1 C049584 CTD increases(expression) NTRK1 C049584 CTD affects(cotreatment) OAT C049584 CTD increases(response to substance) OAT C049584 CTD decreases(expression) ODF4 C049584 CTD increases(expression) OSM C049584 CTD decreases(expression) PAQR7 C049584 CTD decreases(expression) PDCD1 C049584 CTD increases(expression) PDZD7 C049584 CTD increases(expression) PGR C049584 CTD decreases(reaction) PGR C049584 CTD affects(activity) POLH C049584 CTD affects(activity) POLK C049584 CTD affects(cotreatment) POR C049584 CTD increases(response to substance) POR C049584 CTD decreases(expression) POTED C049584 CTD increases(expression) PRKAR2B C049584 CTD increases(metabolic processing) PTGS1 C049584 CTD increases(expression) PTGS2 C049584 CTD decreases(reaction) PTGS2 C049584 CTD increases(metabolic processing) PTGS2 C049584 CTD decreases(expression) RAD23B C049584 CTD increases(phosphorylation) RAF1 C049584 CTD decreases(expression) RAPGEF1 C049584 CTD decreases(phosphorylation) RB1 C049584 CTD decreases(expression) RBM14 C049584 CTD decreases(expression) RIMS4 C049584 CTD decreases(expression) RNF186 C049584 CTD decreases(expression) RNF34 C049584 CTD decreases(expression) RPGR C049584 CTD increases(expression) RPGRIP1 C049584 CTD increases(expression) RRM2B C049584 CTD increases(expression) S100A1 C049584 CTD decreases(expression) SIK1 C049584 CTD decreases(expression) SLAIN2 C049584 CTD decreases(expression) SMYD3 C049584 CTD decreases(expression) SOD2 C049584 CTD increases(expression) SP1 C049584 CTD decreases(expression) SPDYE3 C049584 CTD increases(expression) SRRM2 C049584 CTD increases(expression) STON2 C049584 CTD decreases(activity) SULT1A1 C049584 CTD decreases(response to substance) SULT1A1 C049584 CTD decreases(reaction) SULT1A1 C049584 CTD increases(sulfation) SULT1A1 C049584 CTD decreases(expression) SULT1A1 C049584 CTD affects(cotreatment) SULT1A1 C049584 CTD increases(response to substance) SULT1A1 C049584 CTD increases(activity) SULT1A1 C049584 CTD increases(activity) SULT1A1 C049584 CTD increases(metabolic processing) SULT1A1 C049584 CTD increases(response to substance) SULT1A1 C049584 CTD affects(cotreatment) SULT1A2 C049584 CTD increases(response to substance) SULT1A2 C049584 CTD increases(activity) SULT1A2 C049584 CTD decreases(activity) SULT1A3 C049584 CTD decreases(response to substance) SULT1A3 C049584 CTD increases(response to substance) SULT1A3 C049584 CTD decreases(expression) SYNGR3 C049584 CTD increases(expression) TAF1 C049584 CTD decreases(expression) TBC1D2B C049584 CTD increases(expression) TDRD10 C049584 CTD increases(expression) TMC8 C049584 CTD increases(expression) TNF C049584 CTD decreases(reaction) TNF C049584 CTD decreases(expression) TOP2A C049584 CTD increases(expression) TOR1AIP2 C049584 CTD increases(expression) TP53 C049584 CTD decreases(expression) TRAPPC9 C049584 CTD increases(expression) TTC37 C049584 CTD increases(expression) TTK C049584 CTD increases(expression) TTL C049584 CTD affects(response to substance) UGT1A C049584 CTD increases(expression) UGT1A1 C049584 CTD decreases(activity) UGT1A1 C049584 CTD increases(glucuronidation) UGT1A1 C049584 CTD increases(expression) UGT1A1 C049584 CTD increases(reaction) UGT1A1 C049584 CTD decreases(expression) VPRBP C049584 CTD decreases(expression) WTAP C049584 CTD increases(expression) XPNPEP2 C049584 CTD decreases(expression) YTHDC1 C049584 CTD decreases(expression) ZNF296 C049584 CTD decreases(expression) ZNF624 C049584 CTD decreases(expression) ZNF654 C049584
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