Tan Lab | DSigDB

Gene Set: D4 : CTD - paxilline

Collection

D4 : CTD

Chemical Name

paxilline ( From PubChem : PAXILLINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
435.555 g/mol	3	4	3.9567	True

Structure

InChI

InChI=1S/C27H33NO4/c1-24(2,30)23-20(29)14-18-21(32-23)10-11-25(3)26(4)15(9-12-27(18,25)31)13-17-16-7-5-6-8-19(16)28-22(17)26/h5-8,14-15,21,23,28,30-31H,9-13H2,1-4H3

InChIKey

ACNHBCIZLNNLRS-UHFFFAOYSA-N

Links

Gene (14 / 28)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(phosphorylation)			AKT1		C048220
CTD	decreases(reaction)			AKT1		C048220
CTD	decreases(phosphorylation)			CREB1		C048220
CTD	decreases(reaction)			CREB1		C048220
CTD	increases(abundance)			NR1H3		C048220
CTD	increases(reaction)			NR1H3		C048220
CTD	decreases(reaction)			PTEN		C048220
CTD	increases(phosphorylation)			PTEN		C048220
CTD	decreases(phosphorylation)			TNF		C048220
CTD	decreases(reaction)			TNF		C048220
CTD	increases(phosphorylation)			TNF		C048220
PubChem	None	uM		BCL2L1	-	GI(Protien) :
PubChem	None	uM		BCL2L1	-	GI(Protien) :
PubChem	Potency	uM	31.623	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	0.731	GMNN	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MRGPRX1	-	GI(Protien) :
PubChem	None	uM		NPY1R	-	GI(Protien) :
PubChem	None	uM		NPY1R	-	GI(Protien) :
PubChem	None	uM		NPY1R	-	GI(Protien) :
PubChem	None	uM		NPY2R	-	GI(Protien) :
PubChem	None	uM		NPY2R	-	GI(Protien) :
ChEMBL	Potency	nM	31622.800	EHMT2	-	Target : CHEMBL6032

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