Tan Lab | DSigDB

Gene Set: D4 : CTD - naringenin

Collection

D4 : CTD

Chemical Name

naringenin ( From PubChem : NARINGENIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
272.253 g/mol	3	5	2.5099	True

Structure

InChI

InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2/t13-/m0/s1

InChIKey

FTVWIRXFELQLPI-ZDUSSCGKSA-N

Links

Gene (42 / 114)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			ABCC1		C005273
CTD	decreases(response to substance)			ABCC1		C005273
CTD	increases(export)			ABCC1		C005273
CTD	increases(hydrolysis)			ABCC1		C005273
CTD	increases(reaction)			ABCC1		C005273
CTD	decreases(reaction)			ABCC4		C005273
CTD	increases(export)			ABCC4		C005273
CTD	increases(hydrolysis)			ABCC4		C005273
CTD	increases(reaction)			ABCC4		C005273
CTD	decreases(reaction)			ABCC5		C005273
CTD	decreases(response to substance)			ABCC5		C005273
CTD	increases(export)			ABCC5		C005273
CTD	decreases(reaction)			AHR		C005273
CTD	increases(phosphorylation)			AHR		C005273
CTD	affects(binding)			AKR1C1		C005273
CTD	decreases(activity)			AKR1C1		C005273
CTD	decreases(activity)			AKR1C3		C005273
CTD	decreases(reaction)			AKT1		C005273
CTD	increases(activity)			AKT1		C005273
CTD	affects(binding)			ALPL		C005273
CTD	decreases(reaction)			ALPL		C005273
CTD	increases(activity)			ALPL		C005273
CTD	decreases(reaction)			ARNT		C005273
CTD	increases(phosphorylation)			ARNT		C005273
CTD	affects(cotreatment)			BCHE		C005273
CTD	decreases(activity)			BCHE		C005273
CTD	decreases(reaction)			BCHE		C005273
CTD	decreases(response to substance)			BCL2		C005273
CTD	decreases(reaction)			BCL2		C005273
CTD	increases(activity)			CASP3		C005273
CTD	increases(activity)			CASP9		C005273
CTD	increases(activity)			CTSD		C005273
CTD	increases(expression)			CTSD		C005273
CTD	increases(phosphorylation)			CTSD		C005273
CTD	decreases(reaction)			CXCL8		C005273
CTD	increases(secretion)			CXCL8		C005273
CTD	affects(binding)			CYP19A1		C005273
CTD	decreases(activity)			CYP19A1		C005273
CTD	decreases(activity)			CYP19A1		C005273
CTD	affects(binding)			CYP1A1		C005273
CTD	decreases(activity)			CYP1A1		C005273
CTD	decreases(reaction)			CYP1A1		C005273
CTD	increases(expression)			CYP1A1		C005273
CTD	decreases(activity)			CYP1A1		C005273
CTD	decreases(activity)			CYP1A2		C005273
CTD	affects(binding)			CYP1B1		C005273
CTD	decreases(activity)			CYP1B1		C005273
CTD	decreases(reaction)			CYP2C9		C005273
CTD	increases(hydroxylation)			CYP2C9		C005273
CTD	decreases(activity)			CYP3A4		C005273
CTD	affects(binding)			ESR1		C005273
CTD	decreases(reaction)			ESR1		C005273
CTD	increases(activity)			ESR1		C005273
CTD	affects(activity)			ESR1		C005273
CTD	affects(binding)			ESR1		C005273
CTD	increases(activity)			ESR1		C005273
CTD	affects(binding)			ESR1		C005273
CTD	decreases(expression)			ESR1		C005273
CTD	decreases(reaction)			ESR1		C005273
CTD	affects(binding)			ESR1		C005273
CTD	increases(reaction)			ESR1		C005273
CTD	increases(activity)			ESR1		C005273
CTD	increases(activity)			ESR1		C005273
CTD	increases(phosphorylation)			ESR1		C005273
CTD	increases(expression)			ESR1		C005273
CTD	affects(cotreatment)			ESR1		C005273
CTD	increases(degradation)			ESR1		C005273
CTD	affects(binding)			ESR2		C005273
CTD	increases(activity)			ESR2		C005273
CTD	affects(binding)			ESR2		C005273
CTD	affects(binding)			ESR2		C005273
CTD	decreases(reaction)			ESR2		C005273
CTD	increases(activity)			ESR2		C005273
CTD	decreases(activity)			KCNH2		C005273
CTD	increases(reaction)			KCNH2		C005273
CTD	increases(activity)			PGR		C005273
CTD	increases(expression)			PGR		C005273
CTD	increases(phosphorylation)			PGR		C005273
CTD	increases(expression)			PON1		C005273
CTD	increases(activity)			PSEN2		C005273
CTD	increases(expression)			PSEN2		C005273
CTD	increases(phosphorylation)			PSEN2		C005273
CTD	affects(binding)			SI		C005273
CTD	decreases(activity)			SI		C005273
CTD	decreases(reaction)			SLC16A1		C005273
CTD	increases(uptake)			SLC16A1		C005273
CTD	affects(transport)			SLC2A1		C005273
CTD	decreases(reaction)			SLC2A1		C005273
CTD	decreases(activity)			SLC2A1		C005273
CTD	decreases(reaction)			SULT1A1		C005273
CTD	increases(sulfation)			SULT1A1		C005273
CTD	increases(sulfation)			SULT1A3		C005273
CTD	decreases(reaction)			TNF		C005273
CTD	increases(secretion)			TNF		C005273
CTD	decreases(reaction)			TP53		C005273
CTD	increases(activity)			TP53		C005273
CTD	increases(phosphorylation)			TP53		C005273
CTD	increases(glucuronidation)			UGT1A1		C005273
CTD	increases(glucuronidation)			UGT1A10		C005273
CTD	increases(glucuronidation)			UGT1A7		C005273
CTD	increases(glucuronidation)			UGT1A8		C005273
CTD	increases(glucuronidation)			UGT1A9		C005273
CTD	increases(metabolic processing)			UGT2B15		C005273
CTD	increases(metabolic processing)			UGT2B15		C005273
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
ChEMBL	AC50	nM	3162.280	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	7943.300	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	5011.870	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	5011.900	CYP3A4	-	Target : CHEMBL340

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