Tan Lab | DSigDB

Gene Set: D4 : CTD - bryostatin 1

Collection

D4 : CTD

Chemical Name

bryostatin 1 ( From PubChem : BRYOSTATIN 1 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
905.033 g/mol	4	17	4.2799	False(2/4)

Structure

InChI

InChI=1S/C47H68O17/c1-10-11-12-13-14-15-39(51)62-43-31(22-41(53)58-9)21-34-25-37(28(2)48)61-42(54)24-32(50)23-35-26-38(59-29(3)49)45(6,7)46(55,63-35)27-36-19-30(20-40(52)57-8)18-33(60-36)16-17-44(4,5)47(43,56)64-34/h12-17,20,22,28,32-38,43,48,50,55-56H,10-11,18-19,21,23-27H2,1-9H3

InChIKey

MJQUEDHRCUIRLF-UHFFFAOYSA-N

Links

Gene (10 / 17)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	increases(expression)		BIRC3		C046785
CTD	increases(expression)		CD22		C046785
CTD	decreases(reaction)		CDK1		C046785
CTD	increases(activity)		CDK1		C046785
CTD	decreases(expression)		IL10		C046785
CTD	decreases(expression)		IL12B		C046785
CTD	increases(expression)		IL12B		C046785
CTD	increases(expression)		ITGAX		C046785
CTD	affects(cotreatment)		PRKCA		C046785
CTD	decreases(expression)		PRKCA		C046785
CTD	affects(cotreatment)		PRKCB		C046785
CTD	decreases(expression)		PRKCB		C046785
CTD	affects(cotreatment)		PRKCG		C046785
CTD	decreases(expression)		PRKCG		C046785
ChEMBL	Activity	-	PRKCA	-	Target : CHEMBL299
ChEMBL	Activity	-	PRKCB	-	Target : CHEMBL3045
ChEMBL	Activity	-	PRKCD	-	Target : CHEMBL2996

Download gene sets

gmt, text, Detailed text