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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 1,25-dihydroxy-26,27-dimethylcholecalciferol

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Collection	D4 : CTD
Chemical Name	1,25-dihydroxy-26,27-dimethylcholecalciferol ( From PubChem : 26,27-DIMETHYLCALCITRIOL )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 444.69 g/mol 3 3 6.4849 False(3/4)
Structure
InChI	InChI=1S/C29H48O3/c1-6-29(32,7-2)17-8-10-20(3)25-14-15-26-22(11-9-16-28(25,26)5)12-13-23-18-24(30)19-27(31)21(23)4/h12-13,20,24-27,30-32H,4,6-11,14-19H2,1-3,5H3/b22-12+,23-13-/t20-,24-,25-,26+,27+,28-/m1/s1
InChIKey	SVILWCIGEZESEP-KBNXZVMKSA-N
Links
Gene (5 / 16) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD affects(binding) CDKN1A C046127 CTD increases(activity) CDKN1A C046127 CTD increases(expression) CDKN1A C046127 CTD affects(binding) CYP24A1 C046127 CTD increases(activity) CYP24A1 C046127 CTD increases(expression) CYP24A1 C046127 CTD affects(binding) CYP3A4 C046127 CTD increases(activity) CYP3A4 C046127 CTD increases(expression) CYP3A4 C046127 CTD affects(binding) TRPV6 C046127 CTD increases(activity) TRPV6 C046127 CTD increases(expression) TRPV6 C046127 CTD affects(binding) VDR C046127 CTD increases(activity) VDR C046127 CTD increases(expression) VDR C046127 CTD decreases(reaction) VDR C046127
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