Tan Lab | DSigDB

Gene Set: D4 : CTD - 2-methyl-5-HT

Collection

D4 : CTD

Chemical Name

2-methyl-5-HT ( From PubChem : 2-METHYLSEROTONIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
190.242 g/mol	3	2	2.3834	True

Structure

InChI

InChI=1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3

InChIKey

WYWNEDARFVJQSG-UHFFFAOYSA-N

Links

Gene (10 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(reaction)			CXCL8		C045918
CTD	increases(secretion)			CXCL8		C045918
CTD	affects(binding)			HTR3A		C045918
CTD	increases(activity)			HTR3A		C045918
CTD	increases(reaction)			IL1B		C045918
CTD	increases(secretion)			IL1B		C045918
CTD	increases(reaction)			IL6		C045918
CTD	increases(secretion)			IL6		C045918
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
ChEMBL	AC50	nM	7943.280	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	7943.300	CYP2C19	-	Target : CHEMBL3622

Download gene sets

gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).