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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine

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Collection	D4 : CTD
Chemical Name	3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine ( From PubChem : DIMETHYL-IQX )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 227.265 g/mol 1 5 2.2967 True
Structure
InChI	InChI=1S/C12H13N5/c1-6-4-8-9(15-7(2)5-14-8)10-11(6)17(3)12(13)16-10/h4-5H,1-3H3,(H2,13,16)
InChIKey	LAZSIJHHPMHKQI-UHFFFAOYSA-N
Links
Gene (12 / 15) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(expression) BAX C045421 CTD increases(expression) BCL2 C045421 CTD increases(expression) CDKN1A C045421 CTD increases(expression) CYP1A1 C045421 CTD affects(activity) CYP1A1 C045421 CTD increases(expression) CYP1A2 C045421 CTD increases(activity) CYP1A2 C045421 CTD affects(response to substance) EPS8L3 C045421 CTD increases(expression) GADD45A C045421 CTD decreases(expression) GSTA1 C045421 CTD increases(expression) MDM2 C045421 CTD decreases(expression) TP53 C045421 CTD increases(expression) TP53 C045421 CTD affects(response to substance) UGT1A C045421 CTD increases(expression) UGT1A1 C045421
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