Tan Lab | DSigDB

Gene Set: D4 : CTD - 2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide

Collection

D4 : CTD

Chemical Name

2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide ( From PubChem : N-CHLOROTHYLNITROSOUREA SARCOSINAMIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
222.63 g/mol	2	7	0.8832	True

Structure

InChI

InChI=1S/C6H11ClN4O3/c1-4(5(8)12)9-6(13)11(10-14)3-2-7/h4H,2-3H2,1H3,(H2,8,12)(H,9,13)/t4-/m0/s1

InChIKey

Links

Gene (9 / 19)

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Source	Type	Gene	Other
CTD	increases(cleavage)	CASP3	C044565
CTD	increases(cleavage)	CASP7	C044565
CTD	decreases(expression)	CCND1	C044565
CTD	decreases(activity)	CDK1	C044565
CTD	decreases(expression)	CDK1	C044565
CTD	increases(expression)	CDK1	C044565
CTD	increases(expression)	CDK1	C044565
CTD	increases(phosphorylation)	CDK1	C044565
CTD	decreases(expression)	CDKN1A	C044565
CTD	increases(expression)	CDKN1A	C044565
CTD	affects(cotreatment)	MGMT	C044565
CTD	decreases(response to substance)	MGMT	C044565
CTD	increases(cleavage)	PARP1	C044565
CTD	increases(expression)	TP53	C044565
CTD	increases(expression)	TP53	C044565
CTD	increases(expression)	TP53	C044565
CTD	increases(phosphorylation)	TP53	C044565
CTD	increases(response to substance)	TP53	C044565
CTD	decreases(expression)	WEE1	C044565

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