Tan Lab | DSigDB

Gene Set: D4 : CTD - 24-hydroxycholesterol

Collection

D4 : CTD

Chemical Name

24-hydroxycholesterol ( From PubChem : CEREBROSTEROL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
402.653 g/mol	2	2	6.3595	False(3/4)

Structure

InChI

InChI=1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25+,26+,27-/m1/s1

InChIKey

IOWMKBFJCNLRTC-XWXSNNQWSA-N

Links

Gene (12 / 28)

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Source	Type	Gene	Other
CTD	increases(expression)	ABCA1	C044563
CTD	increases(expression)	ABCA1	C044563
CTD	increases(expression)	ABCG1	C044563
CTD	affects(metabolic processing)	APP	C044563
CTD	increases(activity)	APP	C044563
CTD	decreases(metabolic processing)	APP	C044563
CTD	decreases(secretion)	APP	C044563
CTD	increases(metabolic processing)	APP	C044563
CTD	decreases(abundance)	CYP27A1	C044563
CTD	affects(cotreatment)	CYP3A4	C044563
CTD	increases(expression)	CYP3A4	C044563
CTD	affects(abundance)	CYP46A1	C044563
CTD	increases(chemical synthesis)	CYP46A1	C044563
CTD	increases(metabolic processing)	CYP46A1	C044563
CTD	increases(metabolic processing)	CYP7A1	C044563
CTD	affects(binding)	ESR1	C044563
CTD	decreases(activity)	ESR1	C044563
CTD	decreases(reaction)	ESR1	C044563
CTD	increases(activity)	ESR1	C044563
CTD	affects(binding)	ESR2	C044563
CTD	decreases(activity)	ESR2	C044563
CTD	decreases(reaction)	ESR2	C044563
CTD	increases(activity)	ESR2	C044563
CTD	decreases(activity)	HMGCR	C044563
CTD	affects(cotreatment)	NR1H3	C044563
CTD	increases(expression)	NR1H3	C044563
CTD	increases(expression)	TH	C044563
CTD	increases(phosphorylation)	TH	C044563

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