Tan Lab | DSigDB

Gene Set: D4 : CTD - N,N-diethyl-2-((4-phenylmethyl)phenoxy)ethanamine

Collection

D4 : CTD

Chemical Name

N,N-diethyl-2-((4-phenylmethyl)phenoxy)ethanamine ( From PubChem : TESMILIFENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
283.408 g/mol	0	2	3.998	True

Structure

InChI

InChI=1S/C19H25NO/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17/h5-13H,3-4,14-16H2,1-2H3

InChIKey

Links

Gene (13 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			CD14		C043062
CTD	decreases(expression)			CD33		C043062
CTD	decreases(expression)			CD40		C043062
CTD	decreases(expression)			CD86		C043062
CTD	decreases(expression)			ITGA4		C043062
CTD	decreases(expression)			ITGAX		C043062
CTD	decreases(expression)			LRP1		C043062
CTD	decreases(expression)			PTPRC		C043062
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	23.715	GMNN	-	GI(Protien) :
PubChem	Potency	uM	21.136	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
ChEMBL	AC50	nM	15848.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	15848.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	15848.900	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	15848.900	CYP2C9	-	Target : CHEMBL3397

Download gene sets