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Gene Set: D4 : CTD - ebselen

Collection D4 : CTD
Chemical Name ebselen ( From PubChem : EBSELEN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
274.177 g/mol 0 2 2.0477 True
Structure
InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
InChIKey DYEFUKCXAQOFHX-UHFFFAOYSA-N
Links

Gene (81 / 193)


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Source Type Unit Value Gene PMID Assay Other
CTDdecreases(reaction)ACTA2
C042986
CTDincreases(expression)ACTA2
C042986
CTDdecreases(reaction)ADAM9
C042986
CTDincreases(expression)ADAM9
C042986
CTDdecreases(activity)ALOX5
C042986
CTDdecreases(reaction)CASP3
C042986
CTDincreases(activity)CASP3
C042986
CTDdecreases(reaction)CASP9
C042986
CTDincreases(activity)CASP9
C042986
CTDdecreases(reaction)CXCL8
C042986
CTDincreases(expression)CXCL8
C042986
CTDincreases(secretion)CXCL8
C042986
CTDaffects(binding)EPHX2
C042986
CTDdecreases(activity)EPHX2
C042986
CTDaffects(activity)FOS
C042986
CTDaffects(localization)FOS
C042986
CTDdecreases(reaction)FOS
C042986
CTDdecreases(reaction)HIF1A
C042986
CTDincreases(activity)HIF1A
C042986
CTDincreases(expression)HIF1A
C042986
CTDdecreases(activity)PHOSPHO1
C042986
CTDaffects(activity)RELA
C042986
CTDaffects(localization)RELA
C042986
CTDdecreases(reaction)RELA
C042986
CTDdecreases(reaction)SLC11A2
C042986
CTDincreases(uptake)SLC11A2
C042986
CTDdecreases(response to substance)SOD1
C042986
CTDdecreases(reaction)TGFB1
C042986
CTDincreases(expression)TGFB1
C042986
CTDaffects(binding)XPA
C042986
CTDdecreases(reaction)XPA
C042986
PubChem IC50uM1.101ABHD5-GI(Protien) :
PubChem IC50uM3.410ABHD5-GI(Protien) :
PubChem NoneuMABHD5-GI(Protien) :
PubChem NoneuMABHD5-GI(Protien) :
PubChem NoneuMABHD5-GI(Protien) :
PubChem NoneuMABHD5-GI(Protien) :
PubChem PotencyuM0.126ALDH1A1-GI(Protien) :
PubChem PotencyuM0.224ALDH1A1-GI(Protien) :
PubChem PotencyuM0.447ALDH1A1-GI(Protien) :
PubChem PotencyuM2.512ALOX12-GI(Protien) :
PubChem PotencyuM3.162ALOX12-GI(Protien) :
PubChem PotencyuM0.063ALOX15-GI(Protien) :
PubChem PotencyuM0.398ALOX15-GI(Protien) :
PubChem IC50_MICROMuM1.524ARRB1-GI(Protien) :
PubChem NoneuMARRB1-GI(Protien) :
PubChem NoneuMARRB1-GI(Protien) :
PubChem NoneuMARRB1-GI(Protien) :
PubChem PotencyuM1.413BAZ2B-GI(Protien) :
PubChem PotencyuM25.119CBX1-GI(Protien) :
PubChem NoneuMCTDSP1-GI(Protien) :
PubChem Potency-Replicate_1uM29.849CYP19A1-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM0.126CYP2C19-GI(Protien) :
PubChem PotencyuM1.585CYP2C19-GI(Protien) :
PubChem PotencyuM0.079CYP2C9-GI(Protien) :
PubChem PotencyuM1.000CYP2C9-GI(Protien) :
PubChem PotencyuM1.000CYP2D6-GI(Protien) :
PubChem PotencyuM10.000CYP2D6-GI(Protien) :
PubChem PotencyuM3.981CYP3A4-GI(Protien) :
PubChem PotencyuM25.119CYP3A4-GI(Protien) :
PubChem NoneuMDLD-GI(Protien) :
PubChem PotencyuM0.071EHMT2-GI(Protien) :
PubChem PotencyuM0.501EHMT2-GI(Protien) :
PubChem PotencyuM1.413EHMT2-GI(Protien) :
PubChem Absolute IC50uM1.150EIF4G1-GI(Protien) :
PubChem NoneuMEIF4G1-GI(Protien) :
PubChem NoneuMERAP1-GI(Protien) :
PubChem PotencyuM79.433FEN1-GI(Protien) :
PubChem IC50_MeanuM13.200G6PD-GI(Protien) :
PubChem PotencyuM22.387GBA-GI(Protien) :
PubChem PotencyuM14.125GCK-GI(Protien) :
PubChem PotencyuM14.125GCKR-GI(Protien) :
PubChem PotencyuM25.119GLA-GI(Protien) :
PubChem PotencyuM2.818GLS-GI(Protien) :
PubChem PotencyuM6.310GLS-GI(Protien) :
PubChem PotencyuM18.356GMNN-GI(Protien) :
PubChem PotencyuM12.589GNAI1-GI(Protien) :
PubChem NoneuMGNAI1-GI(Protien) :
PubChem NoneuMGPR183-GI(Protien) :
PubChem NoneuMHKDC1-GI(Protien) :
PubChem NoneuMHKDC1-GI(Protien) :
PubChem NoneuMHNF4A-GI(Protien) :
PubChem PotencyuM0.355HPGD-GI(Protien) :
PubChem PotencyuM0.631HPGD-GI(Protien) :
PubChem PotencyuM0.708HPGD-GI(Protien) :
PubChem NoneuMIDE-GI(Protien) :
PubChem NoneuMIDE-GI(Protien) :
PubChem PotencyuM23.109IDH1-GI(Protien) :
PubChem NoneuMIL1B-GI(Protien) :
PubChem NoneuMITGA4-GI(Protien) :
PubChem PotencyuM0.251KAT2A-GI(Protien) :
PubChem PotencyuM0.355KAT2A-GI(Protien) :
PubChem PotencyuM0.398KAT2A-GI(Protien) :
PubChem PotencyuM0.794KAT2A-GI(Protien) :
PubChem NoneuMMDM2-GI(Protien) :
PubChem NoneuMMDM4-GI(Protien) :
PubChem PotencyuM2.994MPHOSPH8-GI(Protien) :
PubChem PotencyuM5.012MPHOSPH8-GI(Protien) :
PubChem IC50_MeanuM0.190MPI-GI(Protien) :
PubChem IC50uMMPI-GI(Protien) :
PubChem NoneuMMRGPRX1-GI(Protien) :
PubChem Absolute IC50uM0.390NCF1-GI(Protien) :
PubChem NoneuMNCF1-GI(Protien) :
PubChem NoneuMPABPC1-GI(Protien) :
PubChem NoneuMPADI4-GI(Protien) :
PubChem NoneuMPADI4-GI(Protien) :
PubChem IC50_MeanuM0.111PHOSPHO1-GI(Protien) :
PubChem IC50uMPHOSPHO1-GI(Protien) :
PubChem PotencyuM5.799PKM-GI(Protien) :
PubChem PotencyuM6.310PKM-GI(Protien) :
PubChem PotencyuM10.000PKM-GI(Protien) :
PubChem IC50uM3.410PLIN1-GI(Protien) :
PubChem NoneuMPLIN1-GI(Protien) :
PubChem IC50uM1.101PLIN5-GI(Protien) :
PubChem NoneuMPLIN5-GI(Protien) :
PubChem NoneuMPLIN5-GI(Protien) :
PubChem NoneuMPLIN5-GI(Protien) :
PubChem PotencyuM2.994PLK1-GI(Protien) :
PubChem IC50_MeanuM0.672PMM2-GI(Protien) :
PubChem PotencyuM3.162POLB-GI(Protien) :
PubChem NoneuMPRMT1-GI(Protien) :
PubChem NoneuMPTGER2-GI(Protien) :
PubChem PotencyuM12.589RGS12-GI(Protien) :
PubChem NoneuMRGS12-GI(Protien) :
PubChem PotencyuM0.670RGS4-GI(Protien) :
PubChem NoneuMSENP6-GI(Protien) :
PubChem NoneuMSENP7-GI(Protien) :
PubChem NoneuMSENP8-GI(Protien) :
PubChem NoneuMSTK33-GI(Protien) :
PubChem NoneuMTAAR1-GI(Protien) :
PubChem PotencyuM1.413TDP1-GI(Protien) :
PubChem PotencyuM2.512TDP1-GI(Protien) :
PubChem PotencyuM3.264TDP1-GI(Protien) :
PubChem PotencyuM3.264TDP1-GI(Protien) :
PubChem PotencyuM4.467TDP1-GI(Protien) :
PubChem PotencyuM5.012TDP1-GI(Protien) :
PubChem PotencyuM6.684TDP1-GI(Protien) :
PubChem PotencyuM8.414TDP1-GI(Protien) :
PubChem NoneuMTLR9-GI(Protien) :
PubChem PotencyuM2.818VDR-GI(Protien) :
PubChem PotencyuM7.080VDR-GI(Protien) :
PubChem PotencyuM7.943VDR-GI(Protien) :
PubChem PotencyuM17.783VDR-GI(Protien) :
ChEMBLPotencynM125.900ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM446.700ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM223.900ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM3162.300ALOX12
-Target : CHEMBL3687
ChEMBLPotencynM2511.900ALOX12
-Target : CHEMBL3687
ChEMBLPotencynM63.100ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM398.100ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM501.200ALOX15B
-Target : CHEMBL2457
ChEMBLPotencynM631.000ALOX15B
-Target : CHEMBL2457
ChEMBLPotencynM1412.500BAZ2B
-Target : CHEMBL1741220
ChEMBLPotencynM25118.900CBX1
-Target : CHEMBL1741193
ChEMBLPotencynM125.900CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM1584.900CYP2C19
-Target : CHEMBL3622
ChEMBLPotencynM79.400CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM1000.000CYP2C9
-Target : CHEMBL3397
ChEMBLPotencynM1000.000CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM10000.000CYP2D6
-Target : CHEMBL289
ChEMBLPotencynM3981.100CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM25118.900CYP3A4
-Target : CHEMBL340
ChEMBLPotencynM70.800EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM501.200EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM1412.500EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM22387.200GBA
-Target : CHEMBL2179
ChEMBLPotencynM25118.900GLA
-Target : CHEMBL2524
ChEMBLPotencynM707.900HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM354.800HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM631.000HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM316.200HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM2511.900HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM794.300HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM3162.300HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM3981.100HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM398.100KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM251.200KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM794.300KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM354.800KAT2A
-Target : CHEMBL5501
ChEMBLPotencynM8912.500KDM4A
-Target : CHEMBL5896
ChEMBLPotencynM6309.600KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM1258.900KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM398.100KDM4E
-Target : CHEMBL1293226
ChEMBLPotencynM5011.900MPHOSPH8
-Target : CHEMBL1741210
ChEMBLPotencynM2993.500MPHOSPH8
-Target : CHEMBL1741210
ChEMBLIC50nM190.000MPI
-Target : CHEMBL2758
ChEMBLIC50nM111.000PHOSPHO1
-Target : CHEMBL6113
ChEMBLPotencynM6309.600PKM
-Target : CHEMBL1075189
ChEMBLPotencynM5798.800PKM
-Target : CHEMBL1075189
ChEMBLPotencynM10000.000PKM
-Target : CHEMBL1075189
ChEMBLIC50nM672.000PMM2
-Target : CHEMBL1741162
ChEMBLPotencynM3162.300POLB
-Target : CHEMBL2392
Download gene sets gmt, text, Detailed text
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12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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