Tan Lab | DSigDB

Gene Set: D4 : CTD - oxotremorine M

Collection

D4 : CTD

Chemical Name

oxotremorine M ( From PubChem : OXOTREMORINE-M )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
195.281 g/mol	0	2	0.2563	True

Structure

InChI

InChI=1S/C11H19N2O/c1-13(2,3)10-5-4-8-12-9-6-7-11(12)14/h6-10H2,1-3H3/q+1

InChIKey

Links

Gene (13 / 34)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			BCAR1		C042743
CTD	decreases(reaction)			BCAR1		C042743
CTD	increases(phosphorylation)			BCAR1		C042743
CTD	affects(binding)			CHRM1		C042743
CTD	increases(reaction)			CHRM1		C042743
CTD	affects(binding)			CHRM2		C042743
CTD	increases(reaction)			CHRM2		C042743
CTD	affects(binding)			CHRM3		C042743
CTD	increases(reaction)			CHRM3		C042743
CTD	affects(binding)			CHRM4		C042743
CTD	increases(reaction)			CHRM4		C042743
CTD	decreases(reaction)			FOS		C042743
CTD	increases(expression)			FOS		C042743
CTD	affects(cotreatment)			PTK2		C042743
CTD	decreases(reaction)			PTK2		C042743
CTD	increases(phosphorylation)			PTK2		C042743
CTD	increases(reaction)			PTK2		C042743
CTD	affects(cotreatment)			PXN		C042743
CTD	decreases(reaction)			PXN		C042743
CTD	increases(phosphorylation)			PXN		C042743
PubChem	Potency	uM	3.981	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	None	uM		CHRM1	-	GI(Protien) :
PubChem	None	uM		CHRM1	-	GI(Protien) :
PubChem	None	uM		CHRM4	-	GI(Protien) :
PubChem	None	uM		CHRM4	-	GI(Protien) :
PubChem	None	uM		CHRM5	-	GI(Protien) :
PubChem	None	uM		CHRM5	-	GI(Protien) :
PubChem	Potency	uM	0.631	EHMT2	-	GI(Protien) :
PubChem	None	uM		ERAP1	-	GI(Protien) :
PubChem	None	uM		TRHR	-	GI(Protien) :
ChEMBL	Potency	nM	3981.100	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	3981.070	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	631.000	EHMT2	-	Target : CHEMBL6032

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