Tan Lab | DSigDB

Gene Set: D4 : CTD - diallyl trisulfide

Collection

D4 : CTD

Chemical Name

diallyl trisulfide ( From PubChem : DIALLYL TRISULFIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
178.339 g/mol	0	3	3.388	True

Structure

InChI

InChI=1S/C6H10S3/c1-3-5-7-9-8-6-4-2/h3-4H,1-2,5-6H2

InChIKey

UBAXRAHSPKWNCX-UHFFFAOYSA-N

Links

Gene (92 / 144)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCB1		C042577
CTD	increases(expression)			ABCC1		C042577
CTD	decreases(expression)			ABCC3		C042577
CTD	decreases(expression)			ABCC4		C042577
CTD	increases(expression)			ABCC4		C042577
CTD	increases(expression)			ABCC6		C042577
CTD	increases(expression)			AK2		C042577
CTD	decreases(expression)			AKT1		C042577
CTD	increases(expression)			ANXA1		C042577
CTD	affects(localization)			AR		C042577
CTD	decreases(reaction)			AR		C042577
CTD	decreases(expression)			AR		C042577
CTD	decreases(expression)			ATP5H		C042577
CTD	increases(expression)			ATP5H		C042577
CTD	increases(expression)			BAK1		C042577
CTD	increases(expression)			BAX		C042577
CTD	decreases(expression)			BCL2		C042577
CTD	decreases(expression)			BCL2		C042577
CTD	decreases(expression)			BCL2L1		C042577
CTD	increases(expression)			BIRC2		C042577
CTD	increases(expression)			BIRC5		C042577
CTD	increases(expression)			BTF3		C042577
CTD	decreases(expression)			CAPZA1		C042577
CTD	increases(activity)			CASP3		C042577
CTD	increases(expression)			CASP3		C042577
CTD	affects(binding)			CAV1		C042577
CTD	increases(reaction)			CAV1		C042577
CTD	increases(expression)			CCNB1		C042577
CTD	decreases(expression)			CCND1		C042577
CTD	decreases(expression)			CCND1		C042577
CTD	increases(expression)			CCND1		C042577
CTD	increases(degradation)			CDC25C		C042577
CTD	increases(phosphorylation)			CDC25C		C042577
CTD	decreases(reaction)			CDC25C		C042577
CTD	increases(expression)			CDKN1A		C042577
CTD	increases(expression)			CDKN1A		C042577
CTD	increases(expression)			CDKN1B		C042577
CTD	decreases(expression)			CFL1		C042577
CTD	decreases(expression)			CLDN1		C042577
CTD	decreases(expression)			CLDN2		C042577
CTD	decreases(expression)			CLDN3		C042577
CTD	decreases(expression)			CLDN4		C042577
CTD	decreases(expression)			CLDN5		C042577
CTD	decreases(expression)			CSTB		C042577
CTD	decreases(expression)			CYP7A1		C042577
CTD	decreases(expression)			DDT		C042577
CTD	decreases(expression)			EIF4H		C042577
CTD	increases(expression)			ENO1		C042577
CTD	increases(expression)			FAS		C042577
CTD	decreases(expression)			FTH1		C042577
CTD	decreases(reaction)			FTH1		C042577
CTD	increases(degradation)			FTH1		C042577
CTD	decreases(expression)			FTL		C042577
CTD	decreases(reaction)			FTL		C042577
CTD	increases(degradation)			FTL		C042577
CTD	affects(reaction)			FTL		C042577
CTD	increases(expression)			FUBP1		C042577
CTD	increases(expression)			GADD45A		C042577
CTD	decreases(expression)			GAPDH		C042577
CTD	decreases(expression)			GSTP1		C042577
CTD	decreases(expression)			HES1		C042577
CTD	decreases(expression)			HEY1		C042577
CTD	decreases(expression)			HEY2		C042577
CTD	decreases(expression)			HIST1H2BM		C042577
CTD	increases(expression)			HNF4A		C042577
CTD	decreases(expression)			HNRNPA2B1		C042577
CTD	increases(expression)			HNRNPDL		C042577
CTD	increases(expression)			HNRNPH1		C042577
CTD	increases(phosphorylation)			JUN		C042577
CTD	affects(reaction)			JUN		C042577
CTD	decreases(expression)			KRT8		C042577
CTD	affects(reaction)			MAP2K4		C042577
CTD	increases(abundance)			MAP2K4		C042577
CTD	increases(degradation)			MAP2K4		C042577
CTD	affects(expression)			MAP2K7		C042577
CTD	affects(reaction)			MAP2K7		C042577
CTD	increases(degradation)			MAP2K7		C042577
CTD	increases(phosphorylation)			MAP2K7		C042577
CTD	affects(expression)			MAP3K3		C042577
CTD	decreases(expression)			MAPK1		C042577
CTD	decreases(expression)			MAPK3		C042577
CTD	decreases(expression)			MDM2		C042577
CTD	increases(expression)			MIR143		C042577
CTD	increases(expression)			MIR145		C042577
CTD	increases(expression)			MIR200B		C042577
CTD	increases(expression)			MIR200C		C042577
CTD	decreases(expression)			MIR21		C042577
CTD	decreases(activity)			MMP2		C042577
CTD	decreases(activity)			MMP2		C042577
CTD	decreases(expression)			MMP2		C042577
CTD	decreases(expression)			MMP2		C042577
CTD	decreases(expression)			MMP2		C042577
CTD	increases(reaction)			MMP2		C042577
CTD	decreases(expression)			MMP7		C042577
CTD	affects(expression)			MMP9		C042577
CTD	decreases(activity)			MMP9		C042577
CTD	decreases(activity)			MMP9		C042577
CTD	decreases(expression)			MMP9		C042577
CTD	decreases(expression)			MMP9		C042577
CTD	increases(reaction)			MMP9		C042577
CTD	increases(expression)			NDRG1		C042577
CTD	affects(expression)			NOS2		C042577
CTD	affects(binding)			NOS3		C042577
CTD	increases(reaction)			NOS3		C042577
CTD	decreases(degradation)			NOS3		C042577
CTD	increases(expression)			NOS3		C042577
CTD	increases(phosphorylation)			NOS3		C042577
CTD	decreases(reaction)			NOS3		C042577
CTD	decreases(expression)			NOTCH1		C042577
CTD	decreases(activity)			NOTCH1		C042577
CTD	increases(reaction)			NOTCH1		C042577
CTD	decreases(secretion)			NOTCH1		C042577
CTD	increases(expression)			PGK1		C042577
CTD	increases(expression)			PLIN3		C042577
CTD	increases(expression)			PPARA		C042577
CTD	affects(expression)			PTGS2		C042577
CTD	decreases(expression)			PTGS2		C042577
CTD	increases(expression)			S100A11		C042577
CTD	increases(expression)			SRSF1		C042577
CTD	increases(expression)			TAGLN2		C042577
CTD	increases(expression)			TIMP1		C042577
CTD	increases(expression)			TIMP2		C042577
CTD	decreases(expression)			TNF		C042577
CTD	decreases(secretion)			TNF		C042577
CTD	affects(localization)			TP53		C042577
CTD	increases(expression)			TP53		C042577
CTD	decreases(expression)			TPT1		C042577
CTD	decreases(expression)			VDAC1		C042577
CTD	decreases(expression)			VDAC2		C042577
CTD	decreases(expression)			VEGFA		C042577
CTD	decreases(secretion)			VEGFA		C042577
CTD	increases(reaction)			VEGFA		C042577
CTD	decreases(expression)			XIAP		C042577
CTD	decreases(reaction)			XIAP		C042577
CTD	increases(degradation)			XIAP		C042577
CTD	decreases(response to substance)			XIAP		C042577
PubChem	Potency	uM	12.589	ALDH1A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	29.849	ESR1	-	GI(Protien) :
PubChem	Potency	uM	28.184	HPGD	-	GI(Protien) :
PubChem	Potency	uM	22.387	KAT2A	-	GI(Protien) :
PubChem	Potency	uM	25.119	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	28183.800	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	22387.200	KAT2A	-	Target : CHEMBL5501

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