Tan Lab | DSigDB

Gene Set: D4 : CTD - terbinafine

Collection

D4 : CTD

Chemical Name

terbinafine ( From PubChem : TERBINAFINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
291.43 g/mol	0	1	4.8773	True

Structure

InChI

InChI=1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+

InChIKey

Links

Gene (16 / 21)

⊖ Less

Source	Type	Gene	Other
CTD	increases(expression)	CXCL8	C041359
CTD	decreases(reaction)	CXCL8	C041359
CTD	increases(response to substance)	CYP3A4	C041359
CTD	decreases(reaction)	GSTP1	C041359
CTD	increases(metabolic processing)	GSTP1	C041359
CTD	decreases(expression)	IL4	C041359
CTD	decreases(secretion)	IL4	C041359
CTD	decreases(expression)	IL5	C041359
CTD	decreases(secretion)	IL5	C041359
CTD	increases(phosphorylation)	MAPK1	C041359
CTD	increases(phosphorylation)	MAPK3	C041359
CTD	decreases(expression)	MMP2	C041359
CTD	decreases(expression)	MMP9	C041359
CTD	affects(response to substance)	NFE2L2	C041359
CTD	decreases(phosphorylation)	PTK2	C041359
CTD	decreases(phosphorylation)	PXN	C041359
CTD	increases(localization)	RHOA	C041359
CTD	decreases(expression)	RHOB	C041359
CTD	increases(localization)	RHOC	C041359
CTD	increases(expression)	TNF	C041359
CTD	decreases(reaction)	TNF	C041359

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